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. 1959 Feb;38(2):299–305. doi: 10.1172/JCI103802

ON THE RATE OF HYDROCORTISONE CLEARANCE FROM PLASMA IN PREGNANT WOMEN AND IN PATIENTS WITH LAENNEC'S CIRRHOSIS*

Nicholas P Christy 1,2,†, Eleanor Z Wallace 1,2,‡, Wilfred E L Gordon 1,2,§, Joseph W Jailer 1,2
PMCID: PMC293156  PMID: 13631060

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. APPLEBY J. I., NORYMBERSKI J. K. The urinary excretion of 17-hydroxycorticosteroids in human pregnancy. J Endocrinol. 1957 Jul;15(3):310–319. doi: 10.1677/joe.0.0150310. [DOI] [PubMed] [Google Scholar]
  2. ASSALI N. S., GARST J. B., VOSKIAN J. Blood levels of 17-hydroxycorticosteroids in normal and toxemic pregnancies. J Lab Clin Med. 1955 Sep;46(3):385–390. [PubMed] [Google Scholar]
  3. BAYLISS R. I., BROWNE J. C., ROUND B. P., STEINBECK A. W. Plasma-17-hydroxycorticosteroids in pregnancy. Lancet. 1955 Jan 8;268(6854):62–64. doi: 10.1016/s0140-6736(55)90002-7. [DOI] [PubMed] [Google Scholar]
  4. BIRKE G., GEMZELL C. A., PLANTIN L. O., ROBBE H. Plasma levels of 17-hydroxycorticosteroids and urinary excretion pattern of keto-steroids in normal pregnancy. Acta Endocrinol (Copenh) 1958 Apr;27(4):389–402. doi: 10.1530/acta.0.0270389. [DOI] [PubMed] [Google Scholar]
  5. BONGIOVANNI A. M., EBERLEIN W. R. Determination, recovery, identification and renal clearance of conjugated adrenal corticoids in human peripheral blood. Proc Soc Exp Biol Med. 1955 Jun;89(2):281–285. doi: 10.3181/00379727-89-21785. [DOI] [PubMed] [Google Scholar]
  6. BURSTEIN S., SAVARD K., DORFMAN R. I. The in vivo metabolism of hydrocortisone. Endocrinology. 1953 Jul;53(1):88–97. doi: 10.1210/endo-53-1-88. [DOI] [PubMed] [Google Scholar]
  7. CHRISTY N. P., LONGSON D., HORWITZ W. A., KNIGHT M. M. Inhibitory effect of chlorpromazine upon the adrenal cortical response to insulin hypoglycemia in man. J Clin Invest. 1957 Apr;36(4):543–549. doi: 10.1172/JCI103452. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. CHRISTY N. P., WALLACE E. Z., JAILER J. W. Comparative effects of prednisone and of cortisone in suppressing the response of the adrenal cortex to exogenous adrenocorticotropin. J Clin Endocrinol Metab. 1956 Aug;16(8):1059–1074. doi: 10.1210/jcem-16-8-1059. [DOI] [PubMed] [Google Scholar]
  9. CHRISTY N. P., WALLACE E. Z., JAILER J. W. The effect of intravenously-administered ACTH on plasma 17,21-dihydroxy-20-ketosteroids in normal individuals and in patients with disorders of the adrenal cortex. J Clin Invest. 1955 Jun;34(6):899–906. doi: 10.1172/JCI103146. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. DAUGHADAY W. H. Binding of corticosteroids by plasma proteins. V. Corticosteroid-binding globulin activity in normal human beings and in certain disease states. AMA Arch Intern Med. 1958 Feb;101(2):286–290. doi: 10.1001/archinte.1958.00260140118017. [DOI] [PubMed] [Google Scholar]
  11. DAVIS M. E., PLOTZ E. J. Hormonal interrelationships between maternal adrenal, placental and fetal adrenal functions. Obstet Gynecol Surv. 1956 Feb;11(1):1–43. doi: 10.1097/00006254-195602000-00001. [DOI] [PubMed] [Google Scholar]
  12. DEVIS R. L'élimination des corticoïdes au cours de la grossesse. Gynecol Obstet (Paris) 1954;53(1):57–77. [PubMed] [Google Scholar]
  13. ENGLERT E., Jr, BROWN H., WALLACH S., SIMONS E. L. Metabolism of free and conjugated 17-hydroxycorticosteroids in subjects with liver disease. J Clin Endocrinol Metab. 1957 Dec;17(12):1395–1406. doi: 10.1210/jcem-17-12-1395. [DOI] [PubMed] [Google Scholar]
  14. FUKUSHIMA D. K., LEEDS N. S., BRADLOW H. L., KRITCHEVSKY T. H., STOKEM M. B., GALLAGHER T. F. The characterization of four new metabolites of adrenocortical hormones. J Biol Chem. 1955 Jan;212(1):449–460. [PubMed] [Google Scholar]
  15. GRAY C. Excrétion des hormones chez la femme diabétique enceinte. Ann Endocrinol (Paris) 1954;15(1):22–25. [PubMed] [Google Scholar]
  16. Gemzell C. A. Blood levels of 17-hydroxycorticosteroids in normal pregnancy. J Clin Endocrinol. 1953;13:898–902. [PubMed] [Google Scholar]
  17. JAYLE M. F., DESGREZ P., SERPICELLI J., ROZEG J. Dosage des corticoïdes urinaires après hydrolyse biologique. Ann Endocrinol (Paris) 1953;14(5):877–885. [PubMed] [Google Scholar]
  18. MIGEON C. J., BERTRAND J., WALL P. E. Physiological disposition of 4-C14-cortisol during late pregnancy. J Clin Invest. 1957 Sep;36(9):1350–1362. doi: 10.1172/JCI103534. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. PETERSON R. E., SCHMID R. A clinical syndrome associated with a defect in steroid glucuronide formation. J Clin Endocrinol Metab. 1957 Dec;17(12):1485–1488. doi: 10.1210/jcem-17-12-1485. [DOI] [PubMed] [Google Scholar]
  20. PETERSON R. E., WYNGAARDEN J. B., GUERRA S. L., BRODIE B. B., BUNIM J. J. The physiological disposition and metabolic fate of hydrocortisone in man. J Clin Invest. 1955 Dec;34(12):1779–1794. doi: 10.1172/JCI103233. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. PETERSON R. E., WYNGAARDEN J. B. The miscible pool and turnover rate of hydrocortisone in man. J Clin Invest. 1956 May;35(5):552–561. doi: 10.1172/JCI103308. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. ROBINSON H. J., BERNHARD W. G., GRUBIN H., WANNER H., SEWEKOW G. W., SILBER R. H. 17,21-Dihydroxy-20-ketosteroids in plasma during and after pregnancy. J Clin Endocrinol Metab. 1955 Mar;15(3):317–323. doi: 10.1210/jcem-15-3-317. [DOI] [PubMed] [Google Scholar]
  23. SAYERS G. The adrenal cortex and homoestasis. Physiol Rev. 1950 Jul;30(3):241–320. doi: 10.1152/physrev.1950.30.3.241. [DOI] [PubMed] [Google Scholar]
  24. SILBER R. H., PORTER C. C. The determination of 17,21-dihydroxy-20-ketosteroids in urine and plasma. J Biol Chem. 1954 Oct;210(2):923–932. [PubMed] [Google Scholar]
  25. SMITH P. E. The endocrine glands in hypophysectomized pregnant Rhesus monkeys (Macaca mulatta) with special reference to the adrenal glands. Endocrinology. 1955 Mar;56(3):271–284. doi: 10.1210/endo-56-3-271. [DOI] [PubMed] [Google Scholar]
  26. STONER H. B., WHITELEY H. J. The effect of pregnancy on the human adrenal cortex. J Endocrinol. 1957 Jan;14(4):325–334. doi: 10.1677/joe.0.0140325. [DOI] [PubMed] [Google Scholar]
  27. WALLACE E. Z., CHRISTY N. P., JAILER J. W. Clinical application of the simplified Silber-Porter method for determining plasma 17-hydroxycorticosteroids. J Clin Endocrinol Metab. 1955 Sep;15(9):1073–1088. doi: 10.1210/jcem-15-9-1073. [DOI] [PubMed] [Google Scholar]

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