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. 1959 Jun;38(6):916–932. doi: 10.1172/JCI103874

A STUDY OF THE MECHANISM BY WHICH EXERCISE INCREASES THE PULMONARY DIFFUSING CAPACITY FOR CARBON MONOXIDE*,†

Joseph C Ross 1,2,‡, Regina Frayser 1,2, John B Hickam 1,2
PMCID: PMC293242  PMID: 13654528

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BATES D. V., BOUCOT N. G., DORMER A. E. The pulmonary diffusing capacity in normal subjects. J Physiol. 1955 Aug 29;129(2):237–252. doi: 10.1113/jphysiol.1955.sp005350. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BLAKEMORE W. S., FORSTER R. E., MORTON J. W., OGILVIE C. M. A standardized breath holding technique for the clinical measurement of the diffusing capacity of the lung for carbon monoxide. J Clin Invest. 1957 Jan;36(1 Pt 1):1–17. doi: 10.1172/JCI103402. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BONDURANT S., HICKAM J. B., ISLEY J. K. Pulmonary and circulatory effects of acute pulmonary vascular engorgement in normal subjects. J Clin Invest. 1957 Jan;36(1 Pt 1):59–66. doi: 10.1172/JCI103410. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. DOYLE J. T., WILSON J. S., ESTES E. H., WARREN J. V. The effect of intravenous infusions of physiologic saline solution on the pulmonary arterial and pulmonary capillary pressure in man. J Clin Invest. 1951 Apr;30(4):345–352. doi: 10.1172/JCI102450. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. DOYLE J. T., WILSON J. S., LEPINE C., WARREN J. V. An evaluation of the measurement of the cardiac output and of the so-called pulmonary blood volume by the dye-dilution method. J Lab Clin Med. 1953 Jan;41(1):29–39. [PubMed] [Google Scholar]
  6. FILLEY G. F., MACINTOSH D. J., WRIGHT G. W. Carbon monoxide uptake and pulmonary diffusing capacity in normal subjects at rest and during exercise. J Clin Invest. 1954 Apr;33(4):530–539. doi: 10.1172/JCI102923. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. FORSTER R. E., COHN J. E., BRISCOE W. A., BLAKEMORE W. S., RILEY R. L. A modification of the Krogh carbon monoxide breath holding technique for estimating the diffusing capacity of the lung; a comparison with three other methods. J Clin Invest. 1955 Sep;34(9):1417–1426. doi: 10.1172/JCI103191. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. FORSTER R. E. Exchange of gases between alveolar air and pulmonary capillary blood: pulmonary diffusing capacity. Physiol Rev. 1957 Oct;37(4):391–452. doi: 10.1152/physrev.1957.37.4.391. [DOI] [PubMed] [Google Scholar]
  9. FORSTER R. E., FOWLER W. S., BATES D. V., VAN LINGEN B. The absorption of carbon monoxide by the lungs during breath-holding. J Clin Invest. 1954 Aug;33(8):1135–1145. doi: 10.1172/JCI102987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. FORSTER R. E., ROUGHTON F. J., CANDER L., BRISCOE W. A., KREUZER F. Apparent pulmonary diffusing capacity for CO at varying alveolar O2 tensions. J Appl Physiol. 1957 Sep;11(2):277–289. doi: 10.1152/jappl.1957.11.2.277. [DOI] [PubMed] [Google Scholar]
  11. FORSTER R. E., ROUGHTON F. J., KREUZER F., BRISCOE W. A. Photocolorimetric determination of rate of uptake of CO and O2 by reduced human red cell suspensions at 37 degrees C. J Appl Physiol. 1957 Sep;11(2):260–268. doi: 10.1152/jappl.1957.11.2.260. [DOI] [PubMed] [Google Scholar]
  12. FOWLER N. O., WESTCOTT R. N., SCOTT R. C., McGUIRE J. The effect of norepinephrine upon pulmonary arteriolar resistance in man. J Clin Invest. 1951 May;30(5):517–524. doi: 10.1172/JCI102467. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. HICKAM J. B., BLAIR E., FRAYSER R. An open-circuit helium method for measuring functional residual capacity and defective intrapulmonary gas mixing. J Clin Invest. 1954 Sep;33(9):1277–1286. doi: 10.1172/JCI103003. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Hickam J. B., Cargill W. H. EFFECT OF EXERCISE ON CARDIAC OUTPUT AND PULMONARY ARTERIAL PRESSURE IN NORMAL PERSONS AND IN PATIENTS WITH CARDIOVASCULAR DISEASE AND PULMONARY EMPHYSEMA. J Clin Invest. 1948 Jan;27(1):10–23. doi: 10.1172/JCI101912. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Krogh M. The diffusion of gases through the lungs of man. J Physiol. 1915 May 12;49(4):271–300. doi: 10.1113/jphysiol.1915.sp001710. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. LEWIS B. M., FORSTER R. E., BECKMAN E. L. Effect of inflation of a pressure suit on pulmonary diffusing capacity in man. J Appl Physiol. 1958 Jan;12(1):57–64. doi: 10.1152/jappl.1958.12.1.57. [DOI] [PubMed] [Google Scholar]
  17. LINDERHOLM H. On the significance of CO tension in pulmonary capillary blood for determination of pulmonary diffusing capacity with the steady state CO method. Acta Med Scand. 1957 Feb 2;156(6):413–427. doi: 10.1111/j.0954-6820.1957.tb00098.x. [DOI] [PubMed] [Google Scholar]
  18. RILEY R. L., COURNAND A. Analysis of factors affecting partial pressures of oxygen and carbon dioxide in gas and blood of lungs; theory. J Appl Physiol. 1951 Aug;4(2):77–101. doi: 10.1152/jappl.1951.4.2.77. [DOI] [PubMed] [Google Scholar]
  19. ROUGHTON F. J., FORSTER R. E., CANDER L. Rate at which carbon monoxide replaces oxygen from combination with human hemoglobin in solution and in the red cell. J Appl Physiol. 1957 Sep;11(2):269–276. doi: 10.1152/jappl.1957.11.2.269. [DOI] [PubMed] [Google Scholar]
  20. ROUGHTON F. J., FORSTER R. E. Relative importance of diffusion and chemical reaction rates in determining rate of exchange of gases in the human lung, with special reference to true diffusing capacity of pulmonary membrane and volume of blood in the lung capillaries. J Appl Physiol. 1957 Sep;11(2):290–302. doi: 10.1152/jappl.1957.11.2.290. [DOI] [PubMed] [Google Scholar]

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