Skip to main content
NCBI home page
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1959 Jun;38(6):933–938. doi: 10.1172/JCI103875

IN VIVO STUDIES OF 5-HYDROXYINDOLE METABOLISM IN PATIENTS WITH HEPATIC CIRRHOSIS AND IN RATS*,†

Robert M Donaldson Jr 1,‡, Julian Arabehety 1,§, Seymour J Gray 1,ǁ
PMCID: PMC293243  PMID: 13654529

Full text

PDF
933

Images in this article

935Image
on p.935
936Image
on p.936

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ANDERSON J. A., ZIEGLER M. R., DOEDEN D. Banana feeding and urinary excretion of 5-hydroxyindoleacetic acid. Science. 1958 Jan 31;127(3292):236–238. doi: 10.1126/science.127.3292.236. [DOI] [PubMed] [Google Scholar]
  2. AXELROD J., INSCOE J. K., TOMKINS G. M. Enzymatic synthesis of N-glucosyluronic acid conjugates. J Biol Chem. 1958 Jun;232(2):835–841. [PubMed] [Google Scholar]
  3. BESSMAN S. P., MERLIS J. K., BORGES F. Effect of 5-hydroxytryptophane upon electroencephalogram in hepatic coma. Proc Soc Exp Biol Med. 1957 Jul;95(3):502–504. doi: 10.3181/00379727-95-23267. [DOI] [PubMed] [Google Scholar]
  4. BOGDANSKI D. F., PLETSCHER A., BRODIE B. B., UNDENFRIEND S. Identification and assay of serotonin in brain. J Pharmacol Exp Ther. 1956 May;117(1):82–88. [PubMed] [Google Scholar]
  5. CLARK C. T., WEISSBACH H., UDENFRIEND S. 5-Hydroxytryptophan decarboxylase: preparation and properties. J Biol Chem. 1954 Sep;210(1):139–148. [PubMed] [Google Scholar]
  6. DAVIDSON J., SJOERDSMA A., LOOMIS L. N., UDENFRIEND S. Studies with the serotonin precursor, 5-hydroxytryptophan, in experimental animals and man. J Clin Invest. 1957 Nov;36(11):1594–1599. doi: 10.1172/JCI103558. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. DE MEIO R. H., LEWYCKA C., WIZERKANIUK M., SALCIUNAS O. Biological synthesis of sulphuric acid esters of steroid hormones or their metabolites. Biochem J. 1958 Jan;68(1):1–5. doi: 10.1042/bj0680001. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. FRETER K., WEISSBACH H., UDENFRIEND S., WITKOP B. Biochemical and pharmacological studies with D- and L-5-hydroxytryptophan. Proc Soc Exp Biol Med. 1957 Apr;94(4):725–728. doi: 10.3181/00379727-94-23066. [DOI] [PubMed] [Google Scholar]
  9. JEPSON J. B. Paper chromatography of urinary indoles. Lancet. 1955 Nov 12;269(6898):1009–1011. doi: 10.1016/s0140-6736(55)93432-2. [DOI] [PubMed] [Google Scholar]
  10. KOWLESSAR O. D., WILLIAMS R. C., LAW D. H., SLEISENGER M. H. Urinary excretion of 5-hydroxyindolacetic acid in diarrheal states, with special reference to nontropical sprue. N Engl J Med. 1958 Aug 14;259(7):340–341. doi: 10.1056/NEJM195808142590708. [DOI] [PubMed] [Google Scholar]
  11. McISAAC W. M., PAGE I. H. New metabolites of serotonin in carcinoid urine. Science. 1958 Sep 5;128(3323):537–537. doi: 10.1126/science.128.3323.537. [DOI] [PubMed] [Google Scholar]
  12. ROSS G., WEINSTEIN I. B., KABAKOW B. The influence of phenothiazine and some of its derivatives on the determination of 5-hydroxyindoleacetic acid in urine. Clin Chem. 1958 Feb;4(1):66–76. [PubMed] [Google Scholar]
  13. SCHMID R., AXELROD J., HAMMAKER L., SWARM R. L. Congenital jaundice in rats, due to a defect in glucuronide formation. J Clin Invest. 1958 Aug;37(8):1123–1130. doi: 10.1172/JCI103702. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. SNOW P. J., LENNARD-JONES J. E., CURZON G., STACEY R. S. Humoral effects of metastasising carcinoid tumours. Lancet. 1955 Nov 12;269(6898):1004–1009. doi: 10.1016/s0140-6736(55)93431-0. [DOI] [PubMed] [Google Scholar]
  15. UDENFRIEND S., TITUS E., WEISSBACH H., PETERSON R. E. Biogenesis and metabolism of 5-hydroxyindole compounds. J Biol Chem. 1956 Mar;219(1):335–344. [PubMed] [Google Scholar]
  16. UDENFRIEND S., TITUS E., WEISSBACH H. The identification of 5-hydroxy-3-indoleacetic acid in normal urine and a method for its assay. J Biol Chem. 1955 Oct;216(2):499–505. [PubMed] [Google Scholar]
  17. UDENFRIEND S., WEISSBACH H., BOGDANSKI D. F. Increase in tissue serotonin following administration of its precursor 5-hydroxytryptophan. J Biol Chem. 1957 Feb;224(2):803–810. [PubMed] [Google Scholar]
  18. UDENFRIEND S., WEISSBACH H., CLARK C. T. The estimation of 5-hydroxytryptamine (serotonin) in biological tissues. J Biol Chem. 1955 Jul;215(1):337–344. [PubMed] [Google Scholar]
  19. WEISSBACH H., REDFIELD B. G., UDENFRIEND S. Soluble monoamine oxidase; its properties and actions on serotonin. J Biol Chem. 1957 Dec;229(2):953–963. [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES