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. 1960 May;39(5):741–757. doi: 10.1172/JCI104091

THE METABOLISM OF CORTICOSTERONE IN MAN

Ralph E Peterson 1,*, Charles E Pierce 1,*
PMCID: PMC293366  PMID: 14432259

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BALLARD A., HECHT H. H., PLAGER J. E., SAMUELS L. T., TYLER F. H. The rate of metabolism of cortisol in a normal human male. J Clin Endocrinol Metab. 1957 Jan;17(1):1–7. doi: 10.1210/jcem-17-1-1. [DOI] [PubMed] [Google Scholar]
  2. BRADLOW H. L., FRAZELL E. L., GALLAGHER T. F., HELLMAN L. Tracer studies of the absorption and fate of steroid hormones in man. J Clin Invest. 1956 Sep;35(9):1033–1044. doi: 10.1172/JCI103349. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BROWN H., WILLARDSON D. G., SAMUELS L. T., TYLER F. H. 17-Hydroxycorticosteroid metabolism in liver disease. J Clin Invest. 1954 Nov;33(11):1524–1532. doi: 10.1172/JCI103031. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. BUSH I. E. Methods of paper chromatography of steroids applicable to the study of steroids in mammalian blood and tissues. Biochem J. 1952 Jan;50(3):370–378. doi: 10.1042/bj0500370. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. BUSH I. E., SANDBERG A. A. Adrenocortical hormones in human plasma. J Biol Chem. 1953 Dec;205(2):783–793. [PubMed] [Google Scholar]
  6. BUSH I. E. Species differences in adrenocortical secretion. J Endocrinol. 1953 Jan;9(1):95–100. doi: 10.1677/joe.0.0090095. [DOI] [PubMed] [Google Scholar]
  7. BUSH I. E., WILLOUGHBY M. The excretion of allo tetrahydrocortisol in human urine. Biochem J. 1957 Dec;67(4):689–700. doi: 10.1042/bj0670689. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. COPE C. L., BLACK E. G. The behaviour of 14c-cortisol and estimation of cortisol production rate in man. Clin Sci. 1958 Feb;17(1):147–163. [PubMed] [Google Scholar]
  9. DAUGHADAY W. H. Binding of corticosteroids by plasma proteins. III. The binding of corticosteroid and related hormones by human plasma and plasma protein fractions as measured by equilibrium dialysis. J Clin Invest. 1958 Apr;37(4):511–518. doi: 10.1172/JCI103632. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. DECKER H. A., MIGEON C. J., PAUL A. C., SAMUELS L. T., SANDBERG A. A., SMITH D. F. Metabolism of 4-C 14-cortisol in man: body distribution and rates of conjugation. J Clin Endocrinol Metab. 1956 Sep;16(9):1137–1150. doi: 10.1210/jcem-16-9-1137b. [DOI] [PubMed] [Google Scholar]
  11. ELY R. S., HUGHES E. R., KELLEY V. C. Studies of adrenal corticosteroids. I. Estimation of plasma corticosterone and cortisol. J Clin Endocrinol Metab. 1958 Feb;18(2):190–207. doi: 10.1210/jcem-18-2-190. [DOI] [PubMed] [Google Scholar]
  12. ENGEL L. L., CARTER P., FIELDING L. L. Urinary metabolites of administered corticosterone. I. Steroids liberated by glucuronidase hydrolysis. J Biol Chem. 1955 Mar;213(1):99–106. [PubMed] [Google Scholar]
  13. FUKUSHIMA D. K., BRADLOW H. L., DOBRINER K., GALLAGHER T. F. The fate of testosterone infused intravenously in man. J Biol Chem. 1954 Feb;206(2):863–874. [PubMed] [Google Scholar]
  14. FUKUSHIMA D. K., KEMP A. D., SCHNEIDER R., STOKEM M. B., GALLAGHER T. F. Studies in steroid metabolism. XXV. Isolation and characterization of new urinary steroids. J Biol Chem. 1954 Sep;210(1):129–137. [PubMed] [Google Scholar]
  15. GRANT J. K., FORREST A. P., SYMINGTON T. The secretion of cortisol and corticosterone by the human adrenal cortex. Acta Endocrinol (Copenh) 1957 Oct;26(2):195–203. doi: 10.1530/acta.0.0260195. [DOI] [PubMed] [Google Scholar]
  16. HELLMAN L., BRADLOW H. L., ADESMAN J., FUKUSHIMA D. K., KULP J. L., GALLAGHER J. F. The fate of hydrocortisone-4-C14 in man. J Clin Invest. 1954 Aug;33(8):1106–1115. doi: 10.1172/JCI102984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. LEVIN M. E., DAUGHADAY W. H. The influence of the thyroid on adrenocortical function. J Clin Endocrinol Metab. 1955 Dec;15(12):1499–1511. doi: 10.1210/jcem-15-12-1499. [DOI] [PubMed] [Google Scholar]
  18. LEWIS B. A paper-chromatographic technique for the determination of plasma corticosteroids. J Clin Pathol. 1957 May;10(2):148–155. doi: 10.1136/jcp.10.2.148. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. MIGEON C. J., PAUL A. C., SAMUELS L. T., SANDBERG A. A. Metabolism of 4-C14-corticosterone in man. J Clin Endocrinol Metab. 1956 Oct;16(10):1291–1298. doi: 10.1210/jcem-16-10-1291. [DOI] [PubMed] [Google Scholar]
  20. McGUIRE J. S., Jr, TOMKINS G. M. The effects of thyroxin administration on the enzymic reduction of delta 4-3-ketosteroids. J Biol Chem. 1959 Apr;234(4):791–794. [PubMed] [Google Scholar]
  21. NEHER R. Determination of individual adrenocortical steroids. Adv Clin Chem. 1958;VOL(2):127–192. doi: 10.1016/s0065-2423(08)60358-3. [DOI] [PubMed] [Google Scholar]
  22. PEARLMAN W. H. [16-3H]Progesterone metabolism in advanced pregnancy and in oophorectomized-hysterectomized women. Biochem J. 1957 Sep;67(1):1–5. doi: 10.1042/bj0670001. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. PETERSON R. E. Adrenocortical steroid metabolism and adrenal cortical function in liver disease. J Clin Invest. 1960 Feb;39:320–331. doi: 10.1172/JCI104043. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. PETERSON R. E., PIERCE C. E., WYNGAARDEN J. B., BUNIM J. J., BRODIE B. B. The physiological disposition and metabolic fate of cortisone in man. J Clin Invest. 1957 Sep;36(9):1301–1312. doi: 10.1172/JCI103528. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. PETERSON R. E. Plasma corticosterone and hydrocortisone levels in man. J Clin Endocrinol Metab. 1957 Oct;17(10):1150–1157. doi: 10.1210/jcem-17-10-1150. [DOI] [PubMed] [Google Scholar]
  26. PETERSON R. E. The identification of corticosterone in human plasma and its assay by isotope dilution. J Biol Chem. 1957 Mar;225(1):25–37. [PubMed] [Google Scholar]
  27. PETERSON R. E. The influence of the thyroid on adrenal cortical function. J Clin Invest. 1958 May;37(5):736–743. doi: 10.1172/JCI103659. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. PETERSON R. E., WYNGAARDEN J. B., GUERRA S. L., BRODIE B. B., BUNIM J. J. The physiological disposition and metabolic fate of hydrocortisone in man. J Clin Invest. 1955 Dec;34(12):1779–1794. doi: 10.1172/JCI103233. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. PETERSON R. E., WYNGAARDEN J. B. The miscible pool and turnover rate of hydrocortisone in man. J Clin Invest. 1956 May;35(5):552–561. doi: 10.1172/JCI103308. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. ROMANI J. D. Etude de l'élimination urinaire des corticoïdes alpha-cétoliques chez le sujet normal et au cours de la fatigue chronique. II. Fractionnements chromatographiques. C R Seances Soc Biol Fil. 1956;150(11):1928–1932. [PubMed] [Google Scholar]
  31. ROMANI J. D. Etude des métabolites urinaires des corticoïdes chez l'homme; identification des catabolites alpha-cétoliques dans les urines de vingt-quatre heures. C R Seances Soc Biol Fil. 1956 Sep 10;150(4):644–648. [PubMed] [Google Scholar]
  32. ROMANOFF E. B., HUDSON P., PINCUS G. Isolation of hydrocortisone and corticosterone from human adrenal vein blood. J Clin Endocrinol Metab. 1953 Dec;13(12):1546–1548. doi: 10.1210/jcem-13-12-1546. [DOI] [PubMed] [Google Scholar]
  33. SANDBERG A. A., SLAUNWHITE W. R., Jr, ANTONIADES H. N. The binding of steroids and steroid conjugates to human plasma proteins. Recent Prog Horm Res. 1957;13:209–267. [PubMed] [Google Scholar]
  34. SANDBERG A. A., SLAUNWHITE W. R., Jr Transcortin: a corticosteroid-binding protein of plasma. II. Levels in various conditions and the effects of estrogens. J Clin Invest. 1959 Aug;38(8):1290–1297. doi: 10.1172/JCI103904. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. SLAUNWHITE W. R., Jr, SANDBERG A. A. Transcortin: a corticosteroid-binding protein of plasma. J Clin Invest. 1959 Feb;38(2):384–391. doi: 10.1172/JCI103812. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. SOUTHCOTT C. M., SPROULE V. A., McINTOSH H., DARRACH M. Studies on human adrenal steroids. 2. Isolation of 20 alpha-dihydrocorticosterone from the plasma of normal males treated with corticosterone. Can J Biochem Physiol. 1958 Aug;36(8):819–823. [PubMed] [Google Scholar]
  37. SWEAT M. L. Adrenocorticosteroids in peripheral and adrenal venous blood of man. J Clin Endocrinol Metab. 1955 Sep;15(9):1043–1056. doi: 10.1210/jcem-15-9-1043. [DOI] [PubMed] [Google Scholar]
  38. TAMM J., BECKMANN I., VOIGT K. D. Uber Blutsteroide. II. Papierchromatographische Untersuchungen am peripheren menschlichen Blutplasma. Acta Endocrinol (Copenh) 1958 Apr;27(4):403–414. [PubMed] [Google Scholar]
  39. TOMKINS G. M. Enzymatic mechanisms of hormone metabolism. I. Oxidation-reduction of the steroid nucleus. Recent Prog Horm Res. 1956;12:125–133. [PubMed] [Google Scholar]
  40. TOUCHSTONE J. C., BULASCHENKO H., RICHARDSON E. M., DOHAN F. C. The isolation of corticosterone metabolites from the urine of normal men. Arch Biochem Biophys. 1959 Mar;81(1):5–14. doi: 10.1016/0003-9861(59)90170-5. [DOI] [PubMed] [Google Scholar]
  41. UPTON G. V., BONDY P. K. The binding of cortisol by plasma protein. Arch Biochem Biophys. 1958 Nov;78(1):197–205. doi: 10.1016/0003-9861(58)90328-x. [DOI] [PubMed] [Google Scholar]
  42. WERBIN H., BERGENSTAL D. M., GOULD R. G., LEROY G. V. Evaluation of tritium cholesterol as a tracer in man. J Clin Endocrinol Metab. 1957 Mar;17(3):337–345. doi: 10.1210/jcem-17-3-337. [DOI] [PubMed] [Google Scholar]

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