Table 2.
Multivariate models assessing the association between various risk factors and the prevalence of Open-angle Glaucoma in Participants of the Los Angeles Latino Eye Study
| Prevalence of Open-Angle Glaucoma | ||||
|---|---|---|---|---|
| Model with MRE | Model with AL | |||
| Risk Factors | OR (95% CI) | P Value | OR (95% CI) | P Value |
|
Age 40–49 50–59 60–61 70+ |
1.0 1.36 (0.62–2.97) 4.20 (2.11–8.36) 8.06 (3.95–16.44) |
<0.0001 |
1.0 1.25 (0.58–2.71) 3.85 (1.94–7.64) 7.45 (3.66–15.18) |
<0.0001 |
| Gender (male) | 1.35 (0.94–1.95) | 0.11 | 1.27 (0.88–1.84) | 0.20 |
| Presence of Diabetes | 1.14 (0.79–1.66) | 0.48 | 1.15 (0.79–1.67) | 0.47 |
|
Family History of Glaucoma |
1.68 (0.96–2.96) | 0.07 | 1.67 (0.95–2.95) | 0.07 |
|
Presence of Nuclear Opacity (NO) |
1.11 (0.72–1.72) | 0.63 | 1.30 (0.85–1.99) | 0.23 |
| IOP (1 mmHg increase) | 1.19 (1.13–1.25) | <0.0001 | 1.20 (1.14–1.27) | <0.0001 |
|
Corneal Power (1D flatter)* |
1.21 (1.08–1.35) | 0.0007 | 1.14 (1.01–1.28) | 0.04 |
| MRE (≤ −1 D vs > −1 D) | 1.82 (1.20–2.77) | 0.005 | - | - |
| AL (1 mm increase) | - | - | 1.25 (1.03–1.50) | 0.02 |
Multivariate model includes all risk factors significant (p<0.05) in the univariate analysis
Significant P values in bold
OR = odds ratio, CI = confidence interval, D = diopters, IOP = intraocular pressure, MRE = myopic refractive error, AL = axial length, LOCS = Lens Opacities Classification System, Nuclear Opacity = LOCS score grading of NII or greater;
*
Corneal Power measurements were available in only 2594 subjects.