Abstract
The effects of a pnt::Tn5 insertion mutation on the growth of strains lacking phosphoglucoisomerase or glucose 6-phosphate dehydrogenase were examined. The results support the idea that the energy-linked transhydrogenase is an important source of reduced nicotinamide adenine dinucleotide phosphate for Escherichia coli under some conditions.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bragg P. D., Davies P. L., Hou C. Function of energy-dependent transhydrogenase in Escherichia coli. Biochem Biophys Res Commun. 1972 Jun 9;47(5):1248–1255. doi: 10.1016/0006-291x(72)90969-2. [DOI] [PubMed] [Google Scholar]
- Csonka L. N., Fraenkel D. G. Pathways of NADPH formation in Escherichia coli. J Biol Chem. 1977 May 25;252(10):3382–3391. [PubMed] [Google Scholar]
- Fraenkel D. G., Levisohn S. R. Glucose and gluconate metabolism in an Escherichia coli mutant lacking phosphoglucose isomerase. J Bacteriol. 1967 May;93(5):1571–1578. doi: 10.1128/jb.93.5.1571-1578.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Fraenkel D. G. Selection of Escherichia coli mutants lacking glucose-6-phosphate dehydrogenase or gluconate-6-phosphate dehydrogenase. J Bacteriol. 1968 Apr;95(4):1267–1271. doi: 10.1128/jb.95.4.1267-1271.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gerolimatos B., Hanson R. L. Repression of Escherichia coli pyridine nucleotide transhydrogenase by leucine. J Bacteriol. 1978 May;134(2):394–400. doi: 10.1128/jb.134.2.394-400.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hansen E. J., Juni E. Isolation of mutants of Escherichia coli lacking NAD- and NADP-linked malic. Biochem Biophys Res Commun. 1975 Jul 22;65(2):559–566. doi: 10.1016/s0006-291x(75)80183-5. [DOI] [PubMed] [Google Scholar]
- Hanson R. L., Rose C. Genetic mapping of a mutation affecting pyridine nucleotide transhydrogenase in Escherichia coli. J Bacteriol. 1979 Jun;138(3):783–787. doi: 10.1128/jb.138.3.783-787.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kleckner N., Roth J., Botstein D. Genetic engineering in vivo using translocatable drug-resistance elements. New methods in bacterial genetics. J Mol Biol. 1977 Oct 15;116(1):125–159. doi: 10.1016/0022-2836(77)90123-1. [DOI] [PubMed] [Google Scholar]
- Murai T., Tokushige M., Nagai J., Katsuki H. Studies on regulatory functions of malic enzymes. I. Metabolic functions of NAD- and NADP-linked malic enzymes in Escherichia coli. J Biochem. 1972 Jun;71(6):1015–1028. doi: 10.1093/oxfordjournals.jbchem.a129850. [DOI] [PubMed] [Google Scholar]
- Zahl K. J., Rose C., Hanson R. L. Isolation and partial characterization of a mutant of Escherichia coli lacking pyridine nucleotide transhydrogenase. Arch Biochem Biophys. 1978 Oct;190(2):598–602. doi: 10.1016/0003-9861(78)90315-6. [DOI] [PubMed] [Google Scholar]