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. Author manuscript; available in PMC: 2011 Sep 3.
Published in final edited form as: Cell. 2010 Aug 19;142(5):749–761. doi: 10.1016/j.cell.2010.07.040

Figure 2. Structures of the Sema7A/PlexinC1-SemaPSI and A39R/PlexinC1-SemaPSI complexes.

Figure 2

(A) Ribbon models of the Sema7A/PlexinC1-SemaPSI complex in front view (left) and side view (right), with the Sema7A protomers colored in cyan and blue, and the PlexinC1-SemaPSI protomers in pink and magenta. The N-linked glycans are depicted as sticks with carbon atoms colored in green. A cartoon of a membrane is drawn above and below the complex to indicate where the respective proteins would be attached to the cell surfaces.

(B) The structure of an individual PlexinC1-SemaPSI molecule from the complex in two orthogonal views, with each of the 7 β-propeller blades, the extrusion, the flap and the PSI domain individually colored.

(C) Ribbon model of the A39R/PlexinC1-Sema-PSI complex in front view (left) and side view (right), with the A39R protomers colored in yellow and wheat, and the other components colored similarly to panel A.

(D) Ribbon model of an A39R protomer from the free A39R dimer, with the structural modules colored in the same format as PlexinC1 shown in panel (B).

See Table S1 and Figure S2 for crystallographic statistics and structural comparisons.