Abstract
Most mutants selected for derepression of the biotin operon required elevated concentrations of biotin for growth. Mutant extracts were deficient in holoenzyme synthetase activity.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Campbell A., Campillo-Campbell A. D., Barker D. Repression of biotin biosynthesis in Escherichia coli during growth on biotin vitamers. J Bacteriol. 1978 Jul;135(1):90–98. doi: 10.1128/jb.135.1.90-98.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Campbell A., Del Campillo-Campbell A., Chang R. A mutant of Escherichia coli that requires high concentrations of biotin. Proc Natl Acad Sci U S A. 1972 Mar;69(3):676–680. doi: 10.1073/pnas.69.3.676. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Eisenburg M. A., Mee B., Prakash O., Eisenburg M. R. Properties of alpha-dehydrobiotin-resistant mutants of Escherichia coli K-12. J Bacteriol. 1975 Apr;122(1):66–72. doi: 10.1128/jb.122.1.66-72.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
- KOSOW D. P., HUANG S. C., LANE M. D. Propionyl holocarboxylase synthesis. I. Preparation and properties of the enzyme system. J Biol Chem. 1962 Dec;237:3633–3639. [PubMed] [Google Scholar]
- Ketner G., Campbel A. Operator and promoter mutations affecting divergent transcription in the bio gene cluster of Escherichia coli. J Mol Biol. 1975 Jul 25;96(1):13–27. doi: 10.1016/0022-2836(75)90179-5. [DOI] [PubMed] [Google Scholar]
- Moss J., Lane M. D. The biotin-dependent enzymes. Adv Enzymol Relat Areas Mol Biol. 1971;35:321–442. doi: 10.1002/9780470122808.ch7. [DOI] [PubMed] [Google Scholar]
- Pai C. H., Yau H. C. Chromosomal location of mutations affecting the regualtion of biotin synthesis in Escherichia coli. Can J Microbiol. 1975 Jul;21(7):1116–1120. doi: 10.1139/m75-162. [DOI] [PubMed] [Google Scholar]