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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Shock. 2010 Oct;34(4):369–376. doi: 10.1097/SHK.0b013e3181dc40a8

FIG. 1. Sepsis-induced mortality is exacerbated in diabetic (AKITA) mice in comparison to non-diabetic wild type (WT) animals.

FIG. 1

CLP was performed with a 23-gauge needle to produce 40% mortality in WT mice in the acute phase of sepsis. Mortality was monitored for 28 days. The deaths were separated into two groups: acute (days 1–5) or chronic (days 6–28). In AKITAs, 100% mortality was reached by day 5. This was significantly higher (p<0.01 log rank survival) compared to WT mice. n=8 AKITAs; n=28 WT mice.