Table 4.
Fatty acid | Healthy subjects | Type-2 diabetic patients | ||
---|---|---|---|---|
mol% | nmol/mg protein | mol% | nmol/mg | |
16:0 | 33.0 ± 0.9 | 358.7 ± 16.7 | 34.2 ± 0.4 | 347.6 ± 9.5 |
16:1n-7 | 0.3 ± 0.1 | 3.7 ± 0.9 | 0.2 ± 0.1 | 2.3 ± 0.7 |
18:0 | 15.8 ± 0.5 | 154.8 ± 4.9 | 15.4 ± 0.8 | 142.9 ± 9.6 |
18:1n-7 | 1.4 ± 0.3 | 14.0 ± 2.3 | 1.3 ± 0.3 | 11.8 ± 2.5 |
18:1n-9 | 10.9 ± 0.5 | 108.4 ± 6.0 | 11.6 ± 0.4 | 108.0 ± 5.0 |
18:2n-6 | 22.0 ± 0.9 | 220.0 ± 14.1 | 19.4 ± 0.7* | 181.9 ± 10.3* |
18:3n-3 | 0.2 ± 0.0 | 1.5 ± 0.2 | 0.2 ± 0.1 | 2.0 ± 0.7 |
18:3n-6 | 0.1 ± 0.0 | 0.6 ± 0.2 | 0.0 ± 0.0 | 0.3 ± 0.2 |
20:3n-6 | 2.9 ± 0.2 | 26.7 ± 2.2 | 3.4 ± 0.3 | 29.3 ± 2.5 |
20:4n-6 | 7.8 ± 0.7 | 71.4 ± 5.6 | 9.1 ± 1.0 | 78.0 ± 7.7 |
20:5n-3 | 1.2 ± 0.4 | 10.3 ± 2.8 | 0.8 ± 0.2 | 7.0 ± 1.6 |
22:5n-3 | 0.3 ± 0.2 | 2.9 ± 1.4 | 0.3 ± 0.1 | 2.7 ± 0.9 |
22:6n-3 | 3.3 ± 0.5 | 27.6 ± 3.3 | 3.0 ± 0.2 | 24.3 ± 2.1 |
SFA | 49.1 ± 1.0 | 516.7 ± 20.1 | 50.0 ± 0.8 | 493.7 ± 15.7 |
MUFA | 13.2 ± 0.6 | 130.4 ± 7.4 | 13.5 ± 0.4 | 125.3 ± 4.5 |
PUFA | 37.7 ± 0.8 | 361.1 ± 11.6 | 36.4 ± 0.8 | 326.1 ± 9.7 |
Values expressed as mole percent of main fatty acids and nmol/mg protein. are means ± S.E.M. of at least six subjects per group.
p ≤ 0.05 compared with LDL from healthy subjects. MUFA. monounsaturated fatty acids; PUFA. polyunsaturated fatty acids; SFA. saturated fatty acids.