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. Author manuscript; available in PMC: 2010 Sep 29.
Published in final edited form as: Science. 2009 Feb 13;323(5916):934–937. doi: 10.1126/science.1166127

Fig. 2.

Fig. 2

Tryptamine, N-methyltryptamine, and DMT inhibition of photolabeling. Rat liver membranes (100 μg per lane) were suspended in the presence or absence of the protecting drugs. Samples were photolyzed with (A) 1 nM carrier-free [125I]-IACoc or (B) 1 nM carrier-free [125I]IAF. Ten micromolar (+)-pentazocine (P) protected sigma-1 receptor photolabeling, whereas 10 μM haloperidol (H) protected both sigma-1 and sigma-2 receptors. Percent band intensities are shown as compared to controls performed in the absence of protecting ligand (−).