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Indian Journal of Psychiatry logoLink to Indian Journal of Psychiatry
. 2002 Apr-Jun;44(2):150–160.

AGE AT ONSET TYPOLOGY IN OPIOID DEPENDENT MEN: AN EXPLORATORY STUDY

Biswajit De *, Surendra K Mattoo *,*, Debasish Basu ‡
PMCID: PMC2954343  PMID: 21206561

Abstract

This study attempted to apply age at onset typology in ICD-10 diagnosed opioid dependence. The sample comprised 80 men seeking treatment at an addiction clinic. The measures included socio-demographic and clinical profile, Severity of Opioid Dependence Questionnaire, Modified Sensation Seeking Scale, Multiphasic Personality Questionnaire (MPQ) and Family History Assessment Module. A cut-off age of 20/21 years for an early-onset late-onset typology of opioid dependence was obtained using two methods - the modal age at onset method and one-third sample by age at onset method. The early onset group showed significant differences in terms of it being more often younger, urban, unmarried, wage earning or students, using oral opioids (not heroin or injectables), showing higher lifetime use and dependence of sedatives, earlier onset of use and dependence of sedatives and tobacco, and higher global psychopathology in terms of MPQ. The early onset group also showed statistically insignificant trends for lesser use and dependence of alcohol, higher severity of opioid dependence, more legal and less social complications, higher sensation seeking (except boredom susceptibility), and more frequent substance dependence in first degree relatives. The age at onset typology in opioid dependence appears to be feasible and having some similarities to similar typology in alcoholism.

Keywords: Opioid dependence, typology, age at onset, men

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Selected References

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  1. Alterman A. I., McDermott P. A., Cacciola J. S., Rutherford M. J., Boardman C. R., McKay J. R., Cook T. G. A typology of antisociality in methadone patients. J Abnorm Psychol. 1998 Aug;107(3):412–422. doi: 10.1037//0021-843x.107.3.412. [DOI] [PubMed] [Google Scholar]
  2. Anglin M. D., Almog I. J., Fisher D. G., Peters K. R. Alcohol use by heroin addicts: evidence for an inverse relationship. A study of methadone maintenance and drug-free treatment samples. Am J Drug Alcohol Abuse. 1989;15(2):191–207. doi: 10.3109/00952998909092720. [DOI] [PubMed] [Google Scholar]
  3. Babor T. F., Hofmann M., DelBoca F. K., Hesselbrock V., Meyer R. E., Dolinsky Z. S., Rounsaville B. Types of alcoholics, I. Evidence for an empirically derived typology based on indicators of vulnerability and severity. Arch Gen Psychiatry. 1992 Aug;49(8):599–608. doi: 10.1001/archpsyc.1992.01820080007002. [DOI] [PubMed] [Google Scholar]
  4. Berzins J. I., Ross W. F., English G. E., Haley J. V. Subgroups among opiate addicts: a typological investigation. J Abnorm Psychol. 1974 Feb;83(1):65–73. doi: 10.1037/h0036237. [DOI] [PubMed] [Google Scholar]
  5. Bukstein O. G., Brent D. A., Kaminer Y. Comorbidity of substance abuse and other psychiatric disorders in adolescents. Am J Psychiatry. 1989 Sep;146(9):1131–1141. doi: 10.1176/ajp.146.9.1131. [DOI] [PubMed] [Google Scholar]
  6. Burgess P. M., Stripp A. M., Pead J., Holman C. P. Severity of opiate dependence in an Australian sample: further validation of the SODQ. Br J Addict. 1989 Dec;84(12):1451–1459. doi: 10.1111/j.1360-0443.1989.tb03926.x. [DOI] [PubMed] [Google Scholar]
  7. Burke K. C., Burke J. D., Jr, Regier D. A., Rae D. S. Age at onset of selected mental disorders in five community populations. Arch Gen Psychiatry. 1990 Jun;47(6):511–518. doi: 10.1001/archpsyc.1990.01810180011002. [DOI] [PubMed] [Google Scholar]
  8. Buydens-Branchey L., Branchey M. H., Noumair D. Age of alcoholism onset. I. Relationship to psychopathology. Arch Gen Psychiatry. 1989 Mar;46(3):225–230. doi: 10.1001/archpsyc.1989.01810030031004. [DOI] [PubMed] [Google Scholar]
  9. Cadoret R. J., Troughton E., O'Gorman T. W., Heywood E. An adoption study of genetic and environmental factors in drug abuse. Arch Gen Psychiatry. 1986 Dec;43(12):1131–1136. doi: 10.1001/archpsyc.1986.01800120017004. [DOI] [PubMed] [Google Scholar]
  10. Cancrini L., Cingolani S., Compagnoni F., Costantini D., Mazzoni S. Juvenile drug addiction: a typology of heroin addicts and their families. Fam Process. 1988 Sep;27(3):261–271. doi: 10.1111/j.1545-5300.1988.00261.x. [DOI] [PubMed] [Google Scholar]
  11. Chaudhry H. R., Arria A., Tarter R., Chaudhry S., Chaudhry N. Familial history of opium use and reported problems among opium addicts in Pakistan. Br J Addict. 1991 Jun;86(6):785–788. doi: 10.1111/j.1360-0443.1991.tb03105.x. [DOI] [PubMed] [Google Scholar]
  12. Cloninger C. R. Neurogenetic adaptive mechanisms in alcoholism. Science. 1987 Apr 24;236(4800):410–416. doi: 10.1126/science.2882604. [DOI] [PubMed] [Google Scholar]
  13. Craig R. J. Personality characteristics of heroin addicts: a review of the empirical literature with critique--part I. Int J Addict. 1979 May;14(4):513–532. doi: 10.3109/10826087909054599. [DOI] [PubMed] [Google Scholar]
  14. Craig R. J. Personality characteristics of heroin addicts: a review of the empirical literature with critique--part II. Int J Addict. 1979 Jul;14(5):607–626. doi: 10.3109/10826087909041894. [DOI] [PubMed] [Google Scholar]
  15. Foulds G. A., Hassall C. The significance of age of onset of excessive drinking in male alcoholics. Br J Psychiatry. 1969 Sep;115(526):1027–1032. doi: 10.1192/bjp.115.526.1027. [DOI] [PubMed] [Google Scholar]
  16. Gilbert J. G., Lombardi D. N. Personality characteristics of young male narcotic addicts. J Consult Psychol. 1967 Oct;31(5):536–538. doi: 10.1037/h0025022. [DOI] [PubMed] [Google Scholar]
  17. Kern M. F., Kenkel M. B., Templer D. I., Newell T. G. Drug preference as a function of arousal and stimulus screening. Int J Addict. 1986 Feb;21(2):255–265. doi: 10.3109/10826088609063454. [DOI] [PubMed] [Google Scholar]
  18. Marvel G. A., Hartmann B. R. An "economic" theory of addiction, hypomania, and sensation seeking. Int J Addict. 1986 Apr-May;21(4-5):495–508. doi: 10.3109/10826088609083538. [DOI] [PubMed] [Google Scholar]
  19. Pedersen W., Clausen S. E., Lavik N. J. Patterns of drug use and sensation-seeking among adolescents in Norway. Acta Psychiatr Scand. 1989 Apr;79(4):386–390. doi: 10.1111/j.1600-0447.1989.tb10274.x. [DOI] [PubMed] [Google Scholar]
  20. Rounsaville B. J., Kosten T. R., Weissman M. M., Prusoff B., Pauls D., Anton S. F., Merikangas K. Psychiatric disorders in relatives of probands with opiate addiction. Arch Gen Psychiatry. 1991 Jan;48(1):33–42. doi: 10.1001/archpsyc.1991.01810250035004. [DOI] [PubMed] [Google Scholar]
  21. Schuckit M. A., Irwin M. An analysis of the clinical relevance of type 1 and type 2 alcoholics. Br J Addict. 1989 Aug;84(8):869–876. doi: 10.1111/j.1360-0443.1989.tb00759.x. [DOI] [PubMed] [Google Scholar]
  22. Spotts J. V., Shontz F. C. Drugs and personality: dependence of findings on method. Am J Drug Alcohol Abuse. 1986;12(4):355–382. doi: 10.3109/00952998609016876. [DOI] [PubMed] [Google Scholar]
  23. Sutherland G., Edwards G., Taylor C., Phillips G., Gossop M., Brady R. The measurement of opiate dependence. Br J Addict. 1986 Aug;81(4):485–494. doi: 10.1111/j.1360-0443.1986.tb00360.x. [DOI] [PubMed] [Google Scholar]
  24. Varma V. K., Basu D., Malhotra A., Sharma A., Mattoo S. K. Correlates of early- and late-onset alcohol dependence. Addict Behav. 1994 Nov-Dec;19(6):609–619. doi: 10.1016/0306-4603(94)90016-7. [DOI] [PubMed] [Google Scholar]
  25. Volpicelli J. R., Clay K. L., Watson N. T., O'Brien C. P. Naltrexone in the treatment of alcoholism: predicting response to naltrexone. J Clin Psychiatry. 1995;56 (Suppl 7):39–44. [PubMed] [Google Scholar]
  26. Vukov M., Baba-Milkic N., Lecic D., Mijalkovic S., Marinkovic J. Personality dimensions of opiate addicts. Acta Psychiatr Scand. 1995 Feb;91(2):103–107. doi: 10.1111/j.1600-0447.1995.tb09748.x. [DOI] [PubMed] [Google Scholar]
  27. Zuckerman M., Eysenck S., Eysenck H. J. Sensation seeking in England and America: cross-cultural, age, and sex comparisons. J Consult Clin Psychol. 1978 Feb;46(1):139–149. doi: 10.1037//0022-006x.46.1.139. [DOI] [PubMed] [Google Scholar]
  28. de Waele J. P., Gianoulakis C. Effects of single and repeated exposures to ethanol on hypothalamic beta-endorphin and CRH release by the C57BL/6 and DBA/2 strains of mice. Neuroendocrinology. 1993 Apr;57(4):700–709. doi: 10.1159/000126428. [DOI] [PubMed] [Google Scholar]
  29. von Knorring L., von Knorring A. L., Smigan L., Lindberg U., Edholm M. Personality traits in subtypes of alcoholics. J Stud Alcohol. 1987 Nov;48(6):523–527. doi: 10.15288/jsa.1987.48.523. [DOI] [PubMed] [Google Scholar]

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