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Journal of General Internal Medicine logoLink to Journal of General Internal Medicine
. 2010 Jun 22;25(10):1102–1104. doi: 10.1007/s11606-010-1412-z

Leriche Syndrome

Michael Frederick 1,, John Newman 1, Jeffrey Kohlwes 2,
PMCID: PMC2955474  PMID: 20568019

A 58-year-old man was admitted for coronary angiography after several months of worsening angina. After two failed femoral catheterization attempts due to guide-wire obstruction, access was achieved through the right brachial artery. Catheterization revealed severe three-vessel coronary artery disease. An aortogram was performed revealing a complete occlusion of the aorta inferior to the renal arteries. A computed tomography angiography with runoff demonstrated significant collateral circulation with reconstitution of the distal femoral arteries. (see image 1)Inline graphicOn further history, the patient noted bilateral calf and buttock claudication, erectile dysfunction and a 40-pack year smoking history. Despite complete aortic occlusion, the patient had 1+ palpable posterior tibial and dorsalis pedis pulses due to extensive collateralization. (see image 2)Inline graphic

Leriche syndrome is the triad of claudication, impotence and decreased pulses due to aortoiliac occlusion.1 Risk factors include hyperlipidemia, hypertension, diabetes mellitus and smoking. The Ankle Brachial Index is a non-invasive, inexpensive and reliable method to screen patients.2 Treatment is aimed at relieving the symptoms related to aortic occlusion as well as the prevention of proximal propagation of thrombus. Complete aortic occlusion is treated with open bypass surgery although new endoscopic techniques are on the horizon.3 Our patient had a successful three vessel CABG followed 2 months later by aortofemoral bypass. His claudication completely resolved 3 weeks postoperatively.Inline graphic

Conflict of Interest

None disclosed.

Open Access

This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

Contributor Information

Michael Frederick, Phone: +1-805-2642514, Email: Michael.Frederick@ucsf.edu.

Jeffrey Kohlwes, Phone: +1-415-7502035, Email: jeffk@medicine.ucsf.edu.

References

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  • 2.Diehm C, Schuster A, Allenberg JR, Darius H, Haberl R, Lange S, Pittrow D, von Stritzky B, Tepohl G, Trampisch HJ. High prevalence of peripheral arterial disease and co-morbidity in 6880 primary care patients: cross-sectional study. Atherosclerosis. 2004;172(1):95–105. doi: 10.1016/S0021-9150(03)00204-1. [DOI] [PubMed] [Google Scholar]
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