Skip to main content
. Author manuscript; available in PMC: 2010 Oct 16.
Published in final edited form as: Gastroenterology. 2008 Apr 22;135(2):591–600. doi: 10.1053/j.gastro.2008.04.019

Figure 5. Foxq1sb/sb stomach defects specifically reflect Foxq1 gene mutations.

Figure 5

(A) Staining of gastric mucosa from C57BL/6 (left) and Beige (right 2 panels) mice for PAS (left 2 panels) and MUC5AC immunohistochemistry (IHC, far right), showing normal expression of neutral stomach mucins and MUC5AC. Images are taken from the gastric corpus and additional data are shown in Suppl. Fig. 3. (B) Complementation analysis of the Foxq1 gene: examination of Foxq1sb/+ (top row, control) and Foxq1sb/enu (bottom row) stomach corpus for PAS stain (left), and stomach antrum for MUC5AC immunostain (middle), and Muc5ac in situ hybridization (right). The Foxq1sb/enu strain effectively phenocopies Satin (Foxq1sb/sb) mice, and the results hint that the Foxq1enu allele may be hypomorphic. Additional data are shown in Suppl. Fig. 4. All scale bars: 60 μm.