Abstract
This paper highlights the recent research findings which suggest that the old teaching that a grandma! seizure is both necessary and sufficient for the efficacy of electroconvulsive therapy (ECT) is not correct. It is necessary; but not sufficient. The stimulus intensity should be adjusted so that it is far above the seizure threshold in order to get maximum efficacy of ECT.
Keywords: ECT stimulus intensity, seizure threshold
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Selected References
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- Girish K., Prasad K. M., Gangadhar B. N., Janakiramiah N., Subbakrishna D. K., Parameshwara G. Clinical predictors of seizure threshold in bilateral ect. Indian J Psychiatry. 1998 Oct;40(4):327–330. [PMC free article] [PubMed] [Google Scholar]
- Petrides G., Fink M. The "half-age" stimulation strategy for ECT dosing. Convuls Ther. 1996 Sep;12(3):138–146. [PubMed] [Google Scholar]
- Sackeim H. A., Decina P., Kanzler M., Kerr B., Malitz S. Effects of electrode placement on the efficacy of titrated, low-dose ECT. Am J Psychiatry. 1987 Nov;144(11):1449–1455. doi: 10.1176/ajp.144.11.1449. [DOI] [PubMed] [Google Scholar]
- Sackeim H. A., Prudic J., Devanand D. P., Kiersky J. E., Fitzsimons L., Moody B. J., McElhiney M. C., Coleman E. A., Settembrino J. M. Effects of stimulus intensity and electrode placement on the efficacy and cognitive effects of electroconvulsive therapy. N Engl J Med. 1993 Mar 25;328(12):839–846. doi: 10.1056/NEJM199303253281204. [DOI] [PubMed] [Google Scholar]