TABLE 1.
Demographic and laboratory parameters by presence of metabolic syndrome at time of transplant
| No Metabolic Syndrome (N=274) | Metabolic Syndrome (N=366) | p-value | |||
|---|---|---|---|---|---|
| Mean | SD | Mean | SD | ||
| Age (years) | 45.5 | 13.0 | 47.1 | 13.1 | 0.11 |
| Male gender (%) | 56.2% | 59.3% | 0.43 | ||
| African American (%) | 37.6% | 27.0% | 0.005 | ||
| Hepatitis C (%) | 11.3% | 10.7% | 0.79 | ||
| CMV (%) | 67.2% | 70.4% | 0.42 | ||
| Etiology of ESRD | |||||
| HTN (%)a | 75.0% | 69.9% | 0.34 | ||
| PKD (%)a | 9.5% | 15.8% | 0.009 | ||
| Deceased donor (%) | 58.4% | 61.7% | 0.39 | ||
| Preemptive transplant (%) | 15.7% | 14.9% | 0.45 | ||
| BMI (kg/m2) | 26.7 | 7.7 | 31.5 | 10.0 | <0.0001 |
| Glucose (mg/dL) | 86.1 | 23.5 | 95.5 | 27.7 | <0.0001 |
| Triglycerides (mg/dL) | 118.8 | 62.7 | 246.4 | 127.4 | <0.0001 |
| SBP (mm Hg) | 159.2 | 22.9 | 158.2 | 20.9 | 0.59 |
| DBP (mm Hg) | 90.8 | 13.9 | 88.4 | 12.5 | 0.03 |
| HDL (mg/dL) | 49.3 | 14.8 | 36.3 | 12.6 | <0.0001 |
| cLDL (mg/dL) | 93.6 | 32.7 | 97.4 | 40.3 | 0.27 |
| Total cholesterol (mg/dL) | 163.7 | 40.3 | 176.1 | 52.5 | 0.004 |
| Apo A1 (mg/dL) | 125.5 | 30.0 | 113.3 | 30.2 | <0.0001 |
| Apo B (mg/dL) | 72.4 | 21.7 | 85.4 | 28.3 | <0.0001 |
| Ratio of Apo B to Apo A1 | 0.60 | 0.21 | 0.78 | 0.25 | <0.0001 |
| White Blood Cells (x109/L) | 7.6 | 3.3 | 8.1 | 4.9 | 0.15 |
| Calcium (mg/dL) | 9.07 | 1.37 | 9.01 | 3.74 | 0.80 |
| Phosphate (mg/dL) | 5.29 | 1.84 | 5.28 | 1.72 | 0.94 |
| Hematocrit (%) | 35.0% | 4.9% | 35.0% | 6.0% | 0.95 |
| Hemoglobin (g/dL) | 11.7 | 1.6 | 11.8 | 2.1 | 0.50 |
| Platelet Count (x109/L) | 198.4 | 68.1 | 198.6 | 79.1 | 0.98 |
| Blood urea nitrogen (mg/dL) | 48.9 | 22.3 | 47.7 | 20.5 | 0.48 |
| Creatinine (mg/dL) | 8.37 | 4.08 | 8.23 | 3.75 | 0.66 |
| Albumin (g/dL) | 4.14 | 0.47 | 4.16 | 0.43 | 0.88 |
| Weight Gain, 3 months (kg) | 4.97 | 5.90 | 4.16 | 9.01 | 0.48 |
| Weight Gain, 6 months (kg) | 5.82 | 8.36 | 6.60 | 9.32 | 0.60 |
BMI- body mass index, CMV- cytomegalovirus, ESRD- end-stage renal disease, HTN- hypertension, PKD- polycystic kidney disease