Abstract
An epileptic patient on high dose carbamazepine monotherapy received erythromycin from a physician and ketoconazole from a dermatologist. Carbamazepine neurotoxicity developed as a result of a pharmacokinetic interaction between the three drugs. Precautions are suggested to minimize the risk of such drug interactions that span medical specializations.
Keywords: Carbamazepine, drug interaction, neurotoxicity, erythromycin, ketoconazole, metabolic interactions, pharmacokinetic interactions
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