Abstract
A young male with bipolar affective disorder, mania with psychotic features was started on lithium therapy. Four days later, he developed an irregular pulse on a lithium level of 0.45 mmol/L. An ECG showed multiple unifocal ventricular ectopics. The cardiac arrhythmia disappeared when lithium was discountinued.
Keywords: Cardiac, arrhythmia, ventricular, ectopics, lithium
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Selected References
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- Brady H. R., Horgan J. H. Lithium and the heart. Unanswered questions. Chest. 1988 Jan;93(1):166–169. doi: 10.1378/chest.93.1.166. [DOI] [PubMed] [Google Scholar]
- Burggraf G. W. Are psychotropic drugs at therapeutic levels a concern for cardiologists? Can J Cardiol. 1997 Jan;13(1):75–80. [PubMed] [Google Scholar]
- Demers R. G., Heninger G. R. Electrocardiographic T-wave changes during lithium carbonate treatment. JAMA. 1971 Oct 18;218(3):381–386. [PubMed] [Google Scholar]
- Rosenqvist M., Bergfeldt L., Aili H., Mathé A. A. Sinus node dysfunction during long-term lithium treatment. Br Heart J. 1993 Oct;70(4):371–375. doi: 10.1136/hrt.70.4.371. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tangedahl T. N., Gau G. T. Myocardial irritability associated with lithium carbonate therapy. N Engl J Med. 1972 Oct 26;287(17):867–869. doi: 10.1056/NEJM197210262871709. [DOI] [PubMed] [Google Scholar]
- Tilkian A. G., Schroeder J. S., Kao J., Hultgren H. Effect of lithium on cardiovascular performance: report on extended ambulatory monitoring and exercise testing before and during lithium therapy. Am J Cardiol. 1976 Nov 23;38(6):701–708. doi: 10.1016/0002-9149(76)90346-5. [DOI] [PubMed] [Google Scholar]
- Wellens H. J., Cats V. M., Düren D. R. Symptomatic sinus node abnormalities following lithium carbonate therapy. Am J Med. 1975 Aug;59(2):285–287. doi: 10.1016/0002-9343(75)90365-4. [DOI] [PubMed] [Google Scholar]