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. Author manuscript; available in PMC: 2010 Oct 26.

Published in final edited form as: Biomaterials. 2007 Apr 5;28(21):3217–3227. doi: 10.1016/j.biomaterials.2007.03.030

Quantitative analysis of gene expression for OPF hydrogel composites encapsulating rabbit MSCs and TGF-β1-loaded microparticles with different concentrations of TGF-β1 (3 ng/ml, 10 ng/ml, and 16 ng/ml): (A) Collagen type II; (B) Aggrecan; (C) Collagen type I. Data are presented as fold ratio after normalized to GAPDH. The expression level of controls (Day 0) is represented as one. Within a given hydrogel formulation, significantly higher (p<0.05) gene expression than day 0 values (controls) are noted with (#). Samples indicated with (*) had significantly higher gene expression than the other two groups at the same time point (p<0.05). Error bars represent means ± standard deviation with n = 4.

Quantitative analysis of gene expression for OPF hydrogel composites encapsulating rabbit MSCs and TGF-β1-loaded microparticles with different concentrations of TGF-β1 (3 ng/ml, 10 ng/ml, and 16 ng/ml): (A) Collagen type II; (B) Aggrecan; (C) Collagen type I. Data are presented as fold ratio after normalized to GAPDH. The expression level of controls (Day 0) is represented as one. Within a given hydrogel formulation, significantly higher (p<0.05) gene expression than day 0 values (controls) are noted with (#). Samples indicated with (*) had significantly higher gene expression than the other two groups at the same time point (p<0.05). Error bars represent means ± standard deviation with n = 4.