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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Shock. 2009 Nov;32(5):541–547. doi: 10.1097/SHK.0b013e3181a6eda2

Fig.6. β1/2-AR differentially regulate LPS-induced TNF-α and IL-10 production.

Fig.6

Wildtype (n=12) and β1/2−/− (n=18) mice were injected I.p. with 50 mg/kg LPS. At 0, 1 and 3 hours post-injection, serum was collected and analyzed for TNF-α, IL-10 and IL-12p40 concentration by ELISA. Data are expressed as mean ± s.e.m. per group at each time point. Analysis by ANOVA with Bonferroni post test revealed that significant difference between the two groups for serum TNF-α levels at 1 hour (*p<0.0001) and 3 hours (**p<0.05) post-injection, and for serum IL-10 levels at 1 hour post-injection (# p<0.00003).