Abstract
We report here a serendipitous observation of marked variations in blood thrombocyte count without agranulocytosis in a patient being treated with clozapine. Possible mechanisms of this thrombocytopenia and thrombocytosis related to clozapine are discussed, raising questions regarding monitoring of platelet counts alongwith granulocyte counts to prevent serious complications as a result of thrombocytosis or thrombocytopenia.
Keywords: Clozapine, platelet, thrombocytopenia, thrombocytosis, adverse drug reaction
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