Table 3.
Physiological Parameters for the Mouse
| Tissue | Vascular (g) | Extravascular (g) | Flow rate (ml/hour) | |
|---|---|---|---|---|
| Venous | 1.12 | 1.12 (Wish et al., 1950; Crispens, 1975a) | 589.09 (Gjedde and Gjedde, 1980; Sarin et al., 1990; Lindstedt and Schaeffer, 2002; Kober et al., 2004) | |
| Arterial | 0.56 | 0.56 (Wish et al., 1950; Crispens, 1975a) | Same as venous compartment | |
| Lung | 0.04 | 0.11 | 0.14 (Plata and Murphy, 1972; Crispens, 1975b) | 589.09 (Peng et al., 2001) |
| Stomach | 0.02 | 0.10 | 0.12 (Barnett and Widdowson, 1965) | 11.66 (Stott et al., 1983) |
| Spleen | 0.02 | 0.06 | 0.08 (Tsai et al., 2002) | 5.45 (Gerlowski and Jain, 1983; Baxter et al., 1994) |
| Small intestine | 0.09 | 0.64 | 0.73 (Lindstedt and Schaeffer, 2002) | 79.53 (Stott et al., 1983) |
| Large intestine | 0.02 | 0.12 | 0.14 (ten Hove et al., 2002; Melgar et al., 2005) | 21.62 (Stott et al., 1983) |
| Muscle | 0.24 | 8.82 | 9.06 (Calder, 1984) | 153.70 (Lindstedt and Schaeffer, 2002) |
| Adipose | 0.12 | 0.68 | 0.80 (Marningas et al., 1986) | 25.15 (Peng et al., 2001) |
| Skin | 0.07 | 3.74 | 3.82 (Lindstedt and Schaeffer, 2002) | 34.64 (Stott et al., 1983) |
| Bone | 0.04 | 1.05 | 1.09 (Lindstedt and Schaeffer, 2002) | 33.09 (Peng et al., 2001) |
| Heart | 0.01 | 0.10 | 0.11 (Lindstedt and Schaeffer, 2002) | 40.85 (Stott et al., 1983; Barbee et al., 1992) |
| Thymus | 0.00 | 0.06 | 0.06 (Peng et al., 2001) | 4.24 (Peng et al., 2001) |
| Brain | 0.02 | 0.49 | 0.51 (Lindstedt and Schaeffer, 2002) | 31.81 (Stott et al., 1983) |
| Testes | 0.00 | 0.25 | 0.25 (Peng et al., 2001) | 2.47 (Stott et al., 1983) |
| Liver | 0.11 | 0.83 | 0.93 (Lindstedt and Schaeffer, 2002) | 20.13 (Lindstedt and Schaeffer, 2002) |
| Kidney | 0.03 | 0.22 | 0.25 (Tsai et al., 2002) | 107.05 (Lindstedt and Schaeffer, 2002) |
| Tumor | 0.11 | 0.60 | 0.71 (Chakrabarti et al., 2007) | 17.67 (Raczka et al., 1983) |