Three lines cross CMs of forepaw, hindpaw, and nose are demonstrated in the schematic graph (A). The beta value of each voxel along the line was plotted as a function of space in the 1D profile (B). Two lines were projected from each CM, and a total of six 1D spatial profiles were analyzed (A, FP, yellow; HP, green; nose, red). The filtered 1D spatial profile (green) was fitted by a second-order polynomial curve (red) for each line (B). The border-width from the extrapolated borders (B, orange dots) along each line was calculated to estimate the spatial extent of the BOLD response. A significantly expanded BOLD response in the S1 representation of nose in F.A. rats is shown (C). (* means p = 0.01;** p = 0.002; two tail, NSHAM = 6, NF.A.= 9).