Skip to main content
Indian Journal of Psychiatry logoLink to Indian Journal of Psychiatry
. 1996 Jul-Sep;38(3):172–177.

A COMPUTERISED AXIAL TOMOGRAPHIC STUDY OF POSTSTROKE MAJOR DEPRESSIVE DISORDER

Rajeev Kumar 1,, Sunil Datta 2, Chandran Gnanamuthu 3, K Kuruvilla 4
PMCID: PMC2970837  PMID: 21584126

Abstract

32 right handed patients who had developed stroke within six months prior to the study and were free from aphasia and impaired level of consciousness were subjected to detailed neurological and psychiatric evaluation. 30 of them also had CT scan of brain. 9 among the 32 patients (28.I %) had major depression as per DSM III R criteria and 5 among them (15.6%) fulfilled the criteria for major depression with melancholia. Occurrence of depression was not related to the age or sex of the patient or duration or type of stroke. Radiological evidence for stroke was present in 25 out of the 30 who had CT Scan. Though there was no correlation between presence of depression and the involvement of a particular hemisphere, MDD was more prevalent in those who had left frontal and right or left subcortical lesions.

Keywords: Stroke, major depressive disorder, melancholia, CT Scan

Full Text

The Full Text of this article is available as a PDF (283.7 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ebrahim S., Barer D., Nouri F. Affective illness after stroke. Br J Psychiatry. 1987 Jul;151:52–56. doi: 10.1192/bjp.151.1.52. [DOI] [PubMed] [Google Scholar]
  2. Folstein M. F., Folstein S. E., McHugh P. R. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975 Nov;12(3):189–198. doi: 10.1016/0022-3956(75)90026-6. [DOI] [PubMed] [Google Scholar]
  3. Folstein M. F., Maiberger R., McHugh P. R. Mood disorder as a specific complication of stroke. J Neurol Neurosurg Psychiatry. 1977 Oct;40(10):1018–1020. doi: 10.1136/jnnp.40.10.1018. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Gasparrini W. G., Satz P., Heilman K., Coolidge F. L. Hemispheric asymmetries of affective processing as determined by the Minnesota Multiphasic Personality Inventory. J Neurol Neurosurg Psychiatry. 1978 May;41(5):470–473. doi: 10.1136/jnnp.41.5.470. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Labi M. L., Phillips T. F., Greshman G. E. Psychosocial disability in physically restored long-term stroke survivors. Arch Phys Med Rehabil. 1980 Dec;61(12):561–565. [PubMed] [Google Scholar]
  6. Parikh R. M., Robinson R. G., Lipsey J. R., Starkstein S. E., Fedoroff J. P., Price T. R. The impact of poststroke depression on recovery in activities of daily living over a 2-year follow-up. Arch Neurol. 1990 Jul;47(7):785–789. doi: 10.1001/archneur.1990.00530070083014. [DOI] [PubMed] [Google Scholar]
  7. Robinson R. G., Kubos K. L., Starr L. B., Rao K., Price T. R. Mood changes in stroke patients: relationship to lesion location. Compr Psychiatry. 1983 Nov-Dec;24(6):555–566. doi: 10.1016/0010-440x(83)90024-x. [DOI] [PubMed] [Google Scholar]
  8. Robinson R. G., Kubos K. L., Starr L. B., Rao K., Price T. R. Mood disorders in stroke patients. Importance of location of lesion. Brain. 1984 Mar;107(Pt 1):81–93. doi: 10.1093/brain/107.1.81. [DOI] [PubMed] [Google Scholar]
  9. Robinson R. G., Starr L. B., Kubos K. L., Price T. R. A two-year longitudinal study of post-stroke mood disorders: findings during the initial evaluation. Stroke. 1983 Sep-Oct;14(5):736–741. doi: 10.1161/01.str.14.5.736. [DOI] [PubMed] [Google Scholar]
  10. Sinyor D., Amato P., Kaloupek D. G., Becker R., Goldenberg M., Coopersmith H. Post-stroke depression: relationships to functional impairment, coping strategies, and rehabilitation outcome. Stroke. 1986 Nov-Dec;17(6):1102–1107. doi: 10.1161/01.str.17.6.1102. [DOI] [PubMed] [Google Scholar]
  11. Sinyor D., Jacques P., Kaloupek D. G., Becker R., Goldenberg M., Coopersmith H. Poststroke depression and lesion location. An attempted replication. Brain. 1986 Jun;109(Pt 3):537–546. doi: 10.1093/brain/109.3.537. [DOI] [PubMed] [Google Scholar]
  12. Starkstein S. E., Robinson R. G., Price T. R. Comparison of cortical and subcortical lesions in the production of poststroke mood disorders. Brain. 1987 Aug;110(Pt 4):1045–1059. doi: 10.1093/brain/110.4.1045. [DOI] [PubMed] [Google Scholar]
  13. Starkstein S. E., Robinson R. G., Price T. R. Comparison of patients with and without poststroke major depression matched for size and location of lesion. Arch Gen Psychiatry. 1988 Mar;45(3):247–252. doi: 10.1001/archpsyc.1988.01800270061007. [DOI] [PubMed] [Google Scholar]

Articles from Indian Journal of Psychiatry are provided here courtesy of Wolters Kluwer -- Medknow Publications

RESOURCES