Table 3.
Shift in Renal Function With Treatment According to Renal Function
| No. of Patients (%) | |||
|---|---|---|---|
| Renal Function at Baseline | Mild or No RI: CLCr ≥60 mL/min | Moderate RI: CLCr ≥30 mL/min to <60 mL/min | Severe RI: CLCr <30 mL/min |
| Mild or no RI, n=238 | 235 (99) | 1 (0.5) | 2 (1) |
| Moderate RI, n=80 | 56 (70)a | 24 (30) | 0 (0) |
| Severe RI, n=14 | 0 (0) | 12 (86)a | 2 (14) |
| Total, N=332 | 291 (88) | 37 (11) | 4 (1) |
RI indicates renal impairment; CLCr, creatinine clearance.
a
These patients improved with treatment. The best postbaseline renal responses were used.