Skip to main content
Bulletin of the World Health Organization logoLink to Bulletin of the World Health Organization
. 2010 Jun 22;88(11):831–838C. doi: 10.2471/BLT.09.068809

Availability and quality of cause-of-death data for estimating the global burden of injuries

توافر وجودة المعطيات المتعلقة بأسباب الوفيات من أجل تقدير العبء العالمي للإصابات

Disponibilité et qualité des données relatives aux causes de décès dans l’estimation du poids mondial des traumatismes

Disponibilidad y calidad de los datos sobre las causas de defunción para calcular la carga mundial de traumatismos

Доступность и качество данных о причине смерти, используемых для оценки глобального бремени травматизма

探讨用于估计全球伤害造成的医疗负担的死因数据的可用性和质量

Kavi Bhalla a,, James E Harrison b, Saeid Shahraz a, Lois A Fingerhut c; on behalf of the Global Burden of Disease Injury Expert Group
PMCID: PMC2971504  PMID: 21076564

Abstract

Objective

To assess the availability and quality of global death registration data used for estimating injury mortality.

Methods

The completeness and coverage of recent national death registration data from the World Health Organization mortality database were assessed. The quality of data on a specific cause of injury death was judged high if fewer than 20% of deaths were attributed to any of several partially specified causes of injury, such as “unspecified unintentional injury”.

Findings

Recent death registration data were available for 83 countries, comprising 28% of the global population. They included most high-income countries, most countries in Latin America and several in central Asia and the Caribbean. Categories commonly used for partially specified external causes of injury resulting in death included “undetermined intent,” “unspecified mechanism of unintentional injury,” “unspecified road injury” and “unspecified mechanism of homicide”. Only 20 countries had high-quality data. Nevertheless, because the partially specified categories do contain some information about injury mechanisms, reliable estimates of deaths due to specific external causes of injury, such as road injury, suicide and homicide, could be derived for many more countries.

Conclusion

Only 20 countries had high-quality death registration data that could be used for estimating injury mortality because injury deaths were frequently classified using imprecise partially specified categories. Analytical methods that can derive national estimates of injury mortality from alternative data sources are needed for countries without reliable death registration systems.

Introduction

Reliable estimates of the burden of death and disability due to injury are essential for shaping national and global health priorities. Although the quality of the information available in developing countries is relatively poor, past efforts at quantifying the global burden of disease13 have convincingly established that injuries contribute approximately 10% to global mortality and 12% to global morbidity. A study into the global burden of disease was commissioned by The World Bank in 1991 and a new study is currently under way.4 Substantial collaborative efforts by the global injury research community will ensure that the best available evidence is incorporated into new estimates of the global burden of injuries.5 Thus, this is an opportune time to undertake an evaluation of the global data sources used for estimating the global burden of injuries. This paper focuses on the availability and quality of global mortality data reported by national death registration systems to the World Health Organization (WHO) mortality database.6

The WHO mortality database is the largest single repository of international data on causes of death. Our study builds on past work by Mathers et al.,7 who examined the quality of cause-of-death data in this database. They assessed quality by examining the proportion of deaths assigned to ill-defined cause-of-death codes, or “dump” codes. Unfortunately, some of the most important dump codes for injury were not included in their quality assessment. For instance, there was no assessment of code X59 of the International classification of diseases and related health problems, tenth revision (ICD-10), namely “accidental exposure to other and unspecified factors,” which is extensively used in death registers to classify injury deaths. Moreover, the WHO mortality database has grown over the past 5 years and a reassessment of data quality is now due.

Following the lead of Mathers et al.,7 our aim was to assess the availability of recent mortality data, the completeness and coverage of regional death registration, and the quality of data derived from injury dump codes. In addition, we discuss the effect of data quality on the reliability of estimates of deaths due to road traffic injury, suicide and homicide.

Methods

Availability of mortality data

We obtained death registration data for a range of countries from the publicly available WHO mortality database (21 April 2009 update).6 The database includes details of deaths registered by national civil registration systems in which the underlying cause of death is coded by the relevant national authority in accordance with ICD rules.8 The analysis included only WHO member countries (listed at: http://www.who.int/countries) for which data were available from after 2000. For most countries, the latest data available were coded using ICD-10. For some, however, the latest available data were classified using the ICD-9 basic tabulation list, which is not adequate for estimating injury mortality, as subsequently discussed. We also included data classified using detailed ICD-9 codes from countries that made such data available to WHO: Guyana, Kiribati, the Netherlands (for Aruba), Saint Vincent and the Grenadines, Singapore, Slovenia and Thailand.

Completeness of registration

The completeness of national death registration was quantified by comparing the number of deaths recorded by death registration data for each country with estimates of projected mortality from the United Nations Population Division.9 Clearly such estimates of completeness are only crude indicators and should not be used for deriving incidence rates for cause-specific mortality. Nevertheless, they do provide some indication of the level of completeness of death registration in each country. In our study, we judged completeness to be high when it was greater than 80% of the expected value, medium when between 60% and 80%, and low otherwise.

Data quality

We classified all injury deaths using 48 categories of specified external causes of death, which constitute the reporting categories recommended by the injury expert group of the 2005 Global Burden of Diseases, Injuries and Risk Factors Study (i.e. the GBD Injury Expert Group),10 and 21 categories of partially specified external causes (Table 1, available at: http://www.who.int/bulletin/volumes/88/11/09-068809). Several countries coded the cause of death using condensed versions of ICD-9 and ICD-10, which do not contain sufficient detail to classify injury deaths according to the full list of external causes of injury shown in Table 1. In addition, these condensed versions group together dump codes with imprecise definitions. For example, the ICD-10 basic tabulation list includes the code X59, for unspecified unintentional injury, in the category 1103 (i.e. all other external causes). The impossibility of separating dump codes means that deaths classified using these codes cannot be reassigned to specified causes and, consequently, the incidence of these causes cannot be estimated. Thus, we excluded countries that used basic tabulation lists from further quality assessment.

Table 1. Categories of specified and partially specified external causes of death used to classify deaths due to injurya.

Specified external causes of death Detailed category Code ICD-10 codeb ICD-9 codeb
Unintentional
Road injury Pedestrian 1 V01–V04, V06, V09 E811–825 (0.7 subsections only), E826–829 (0.0 subsections only)
Bicyclist 2 V10–V19 E810–825 (0.6 subsections only), E826–829 (0.1 subsections only)
Two-wheeler riderc 3 V20–V29 E810–825 (0.2 and 0.3 subsections only)
Three-wheeler occupantc 4 V30–V39
Car occupantd 5 V40–V49 E810–825 (0.0 and 0.1 subsections only)
Van occupantd 6 V50–V59
Truck occupantd 7 V60–V69
Bus occupantd 8 V70–V79
Other road injury 9 V80, V82–V85 E810–825 (0.4, 0.5 and 0.8 subsections only), E826–829 (0.2, 0.3, 0.4 and 0.8 subsections only)
Rail transport injury Rail 10 V05, V81 E800–807, E810.7
Other transport injury Other transport 11 V86, V91, V93–V98 E831, E833–838, E843
Fall Fall 12 W00–W19 E880–886, E888, E929.3
Threats to breathing Drowning 13 V90, V92, W65–W74 E830, E832, E910
Other threats to breathing 14 W75–W84 E911–913
Fire Fire 15 X00–X19 E890–899, E924, E929.4
Mechanical force Firearm 16 W32–W34 E922
Sharp object 17 W25–W29, W45–W46 E920
Machinery 18 W24, W30–W31 E919
Poisoning Gas 19 X46–X47 E862, E867–869
Pesticide 20 X48 E863
Other poison 21 X40–X45, X49 E850–858, E860–861, E864–866, E929.2
Adverse effects of medical treatment Adverse effects of medical treatment 22 Y40–Y84, Y88 E870–879, E930–949
Animal contact Animal contact 23 W53–W59, X20–X27, X29 E905.0–E905.6, E905.8, E905.9, E906
Forces of nature Forces of nature 24 X30–X39 E900–904.9 (excluding E900.1 and E901.1), E907–909, E929.5
Other unintentional Other unintentional 25 W20–W23, W35–W44, W49–W52, W60–W64, W85–W99, X28, X50–X58 E840, E841, E842, E844–848, E900.1, E901.1, E902–904, E905.7, E914–918, E921, E923, E925–928.8, E929.8
Intentional, self-inflicted
Fall Fall 26 X80 E957
Threats to breathing Drowning 27 X71 E954
Other threats to breathing 28 X70 E953
Fire Fire 29 X76–X77 E958.1
Mechanical force Firearm 30 X72–X74 E955 (except E955.5)
Sharp object 31 X78 E956
Poisoning Gas 32 X67 E951–952
Pesticide 33 X68 E950.6
Other poison 34 X60–X66, X69 E950.0–950.5, E950.7–950.9
Other self-inflicted injury Other self-inflicted injury 35 X75, X79, X81–X83 E955.5, E958.0, E958.2–958.8
Intentional, interpersonal
Fall Fall 36 Y01 E968.1
Threats to breathing Drowning 37 X92 E964
Other threats to breathing 38 X91 E963
Fire Fire 39 X97–X98 E968.0
Mechanical force Firearm 40 X93–X95 E965.0–965.4, E968.6
Sharp object 41 X99 E966
Poisoning Gas 42 X88 E962.2
Pesticide 43 X87 NAe
Other poison 44 X85–X86, X89–X90 E961, E962.0, E962.1, E962.9
Other interpersonal injury Other interpersonal injury 45 X96, Y00, Y02–Y08 E960, E965.5–965.9, E967, E968.2–968.5, E968.7–968.8
Intentional, collective violence
Collective violence Collective violence 46 Y36 E979, E990–998
Intentional, legal intervention
Mechanical force Firearm 47 Y35.0 E970
Other legal intervention Other legal intervention 48 Y35.1–Y35.6 E971–975, E978
Partially specified external causes of death
Partially specified, undetermined intent, and unspecified cause
Road injury Unspecified unintentional road injury not including pedestrian or bicyclist 49 V87–V88 E810–825 (0.9 subsections only)
Unspecified unintentional road injury 50 V89, Y85.0 E826–829 (0.9 subsections only), E929.0
Transport injury Unspecified unintentional transport injury 51 V99, Y85.9 E929.1
Non-transport injury Unspecified unintentional non-transport injury 52 Y86 NA
Unintentional injury Unspecified unintentional injury 53 X59 E887, E928.9, E929.9
Self-inflicted injury Unspecified self-inflicted injury 54 X84, Y87.0 E958.9, E959
Interpersonal injury Unspecified interpersonal injury 55 Y09, Y87.1 E968.9, E969
Fall Undetermined intent – fall 56 Y30 E987
Drowning Undetermined intent – drowning 57 Y21 E984
Threats to breathing other than drowning Undetermined intent – threats to breathing other than drowning 58 Y20 E983
Fire Undetermined intent – fire 59 Y26–Y27 E988.1–988.2
Mechanical force Undetermined intent – firearm 60 Y22–Y24 E985.0–985.4, E985.6–985.7
Undetermined intent – sharp object 61 Y28 E986
Poisoning Undetermined intent – gas 62 Y17 E981–982
Undetermined intent – pesticide 63 Y18 E980.7
Undetermined intent – other poison 64 Y10–Y16, Y19 E980.0–980.6, E980.8, E980.9, E988.7
Other injury Undetermined intent – other 65 Y25, Y29, Y31–Y33 E985.5, E988.0, E988.3–988.6, E988.8
All injuries Undetermined intent – unspecified 66 Y34, Y87.2 E988.9, E989
Collective violence Sequelae of collective violence 67 Y89.1 E999
Legal intervention Unspecified legal intervention 68 Y35.7, Y89.0 E976–977
All injury Unspecified injury mechanism 69 Y89.9 NA

ICD, International classification of diseases and related health problems; NA, not applicable.

a These ICD-based definitions of external causes of death were developed by the injury expert group of the 2005 Global Burden of Diseases, Injuries and Risk Factors Study.10

b There are also ICD codes outside the injury chapter that can include injury deaths. We used ICD-10 codes R95–R99 and ICD-9 codes 797–799 for the broadest unspecified cause-of-death category.

c ICD-9 does not distinguish between the riders and occupants of motorized two- and three-wheeler vehicles (i.e. codes 3 and 4).

d ICD-9 does not distinguish between occupants of different four-wheeled vehicles (codes 5–8).

e Poisoning due to pesticides is included with other poisoning in ICD-9 (code 44)

Data quality was assessed by determining the proportion of deaths that were classified as belonging to various partially specified categories: the quality of the data improves as the proportion of deaths assigned to partially specified categories decreases. Moreover, the partially specified categories may form a hierarchy in terms of their information content. This hierarchy is related to the specificity of the definition of each category. For example, the death of a car occupant who was killed in a road traffic accident may be coded using any of the following categories in a hierarchy of partially specified categories whose definition shows less specificity towards the end of the list:

  1. unspecified road injury not including a pedestrian or bicyclist (ICD-10 codes: V87–V88);

  2. unspecified unintentional road injury (ICD-10 codes: V89, Y85.0);

  3. unspecified unintentional transport injury (ICD-10 codes: V99, Y85.9);

  4. unspecified unintentional injury (ICD-10 code: X59);

  5. unspecified injury mechanism (ICD-10 code: Y89.9);

  6. unknown cause of death (ICD-10 codes: R95–R99).

To determine data quality, we computed the proportion of deaths in each partially specified category relative to the corresponding total number of deaths at that level of specificity: e.g. the proportion of road injuries recorded as an unspecified unintentional road injury. Data quality was rated as high when this proportion was smaller than 20%.

Finally, we examined the distribution of deaths classified as belonging to the partially specified categories to determine the circumstances in which the data can, nevertheless, be used to derive reliable estimates of mortality for various specific external causes of death. The countries for which deaths due to road injury, homicide and suicide can be reliably estimated are given as an illustrative example.

Results

Availability of mortality data

Table 2 (available at: http://www.who.int/bulletin/volumes/88/11/09-068809) summarizes the availability of death registration data in the WHO mortality database for countries in the 21 different regions of the world defined by the 2005 Global Burden of Diseases, Injuries and Risk Factors Study.10 For each country, the most recent year for which data are available and the number of years of data availability are listed. In all, 83 countries met the inclusion criteria. They accounted for 28% of the global population. Recent data were available from most countries in high-income regions except for a few notable exceptions: Switzerland used a basic tabulation list and no recent data were available from Belgium. The coverage of death registration data in low- and middle-income regions was more irregular. Three of the four Asian regions (i.e. South, South-East and East Asia) were severely underrepresented, with less than 15% of the regional population covered. The continent of Africa was even less well covered. Data from sub-Saharan Africa were available for only one country (i.e. South Africa). However, low- and middle-income countries in Latin America and the Caribbean were well represented, with over 80% of the population covered. The availability of injury data from eastern Europe, central Europe and central Asia was limited, primarily because of the use of basic tabulation lists.

Table 2. Death registration data available in the WHO mortality database, 2009.

Regiona Death registration data available
Country (most recent year with data available, number of years of data availability)b,c,d
Asia Pacific, high-income countries Japan (2007, 13), Republic of Korea (2006, 12), Singapore (2003, 13);
Country with no data, comprising 0.2% of the regional population: Brunei Darussalam
Central Asia Azerbaijan (2007, 1), Georgia (2001, 4), Kyrgyzstan (2006, 7), Uzbekistan (2005, 2);
Countries with no data, comprising 42% of the regional population: Armenia, Kazakhstan, Mongolia, Tajikistan, Turkmenistan
East Asia China, Hong Kong Special Administrative Region (2007, 7)
Countries with no data, comprising 99.5% of the regional population: China,e Democratic People's Republic of Korea.
South Asia Countries with no data, comprising 100% of the regional population: Afghanistan, Bangladesh, Bhutan, India,e Nepal, Pakistan
South-East Asia Maldives (2005, 6), Mauritius (2007, 10), Thailand (2002, 11);
Countries with no data, comprising 89% of the regional population: Cambodia, Indonesia, Lao People's Democratic Republic, Malaysia, Myanmar, Philippines, Seychelles, Sri Lanka, Timor-Leste, Viet Nam
Australasia Australia (2004, 8), New Zealand (2005, 9);
Countries with no data: none
Caribbean Antigua and Barbuda (2006, 7), Bahamas (2002, 4), Barbados (2003, 4), Belize (2001, 5), Bermuda (2002, 7), Cuba (2006, 7), Dominica (2004, 5), Dominican Republic (2004, 8), Grenada (2005, 5), Guyana (2005, 9), Haiti (2003, 5), Saint Kitts and Nevis (2005, 10), Saint Lucia (2002, 7), Saint Vincent and the Grenadines (2004, 6), Suriname (2005, 8), Trinidad and Tobago (2002, 4);
Country with no data, comprising 6% of the regional population: Jamaica
Central Europe Croatia (2006, 12), Czech Republic (2007, 14), Hungary (2005, 10), Poland (2006, 8), Romania (2007, 9), Serbia (2007, 10), Slovakia (2005, 12), Slovenia (2007, 23);
Countries with no data, comprising 14% of the regional population: Albania, Bosnia and Herzegovina, Bulgaria, Montenegro, The former Yugoslav Republic of Macedonia
Eastern Europe Estonia (2005, 9), Latvia (2007, 12), Lithuania (2007, 10), the Republic of Moldova (2007, 12);
Countries with no data, comprising 95% of the regional population: Belarus, Russian Federation, Ukraine
Western Europe Austria (2007, 9), Cyprus (2006, 2), Denmark (2006, 13), Finland (2007, 12), France (2006, 10), Germany (2006, 9), Greece (2006, 9), Iceland (2007, 12), Ireland (2007, 11), Israel (2005, 10), Italy (2006, 9), Luxembourg (2005, 8), Malta (2007, 13), Netherlands (2007, 12), Norway (2006, 11), Portugal (2003, 5), San Marino (2000, 6), Spain (2005, 9), Sweden (2006, 11), United Kingdom (2007, 9);
Countries with no data, comprising 4% of the regional population: Andorra, Belgium, Monaco, Switzerland
Latin America – Andean countries Ecuador (2006, 10), Peru (2000, 2);
Country with no data, comprising 18% of the regional population: Bolivia
Central Latin America Colombia (2005, 8), Costa Rica (2006, 10), El Salvador (2006, 10), Guatemala (2006, 7), Mexico (2006, 9), Nicaragua (2005, 9), Panama (2006, 8), Venezuela (2005, 10);
Country with no data, comprising 3% of the regional population: Honduras
Southern Latin America Argentina (2005, 9), Chile (2005, 9), Uruguay (2004, 6);
Countries with no data: none
Tropical Latin America Brazil (2005, 10), Paraguay (2004, 9);
Countries with no data: none
North Africa and the Middle East Bahrain (2001, 5), Egypt (2000, 1), Kuwait (2002, 8);
Countries with no data, comprising 81% of the regional population: Algeria, Islamic Republic of Iran, Iraq, Jordan, Lebanon, Libyan Arab Jamahiriya, Morocco, Oman, Qatar, Saudi Arabia, Syrian Arab Republic, Tunisia, Turkey, United Arab Emirates, Yemen
North America, high-income countries Canada (2004, 8), United States of America (2005, 9);
Countries with no data: none
Oceania Kiribati (2001, 11);
Countries with no data, comprising 99% of the regional population: Cook Islands, Fiji, Marshall Islands, Federated States of Micronesia, Nauru, Palau, Papua New Guinea, Samoa, Solomon Islands, Tonga, Tuvalu, Vanuatu
Southern sub-Saharan Africa South Africa (2005, 10);
Countries with no data, comprising 30% of the regional population: Botswana, Lesotho, Namibia, Swaziland, Zimbabwe
Central sub-Saharan Africa Countries with no data, comprising 100% of the regional population: Angola, Central African Republic, Congo, Democratic Republic of the Congo, Equatorial Guinea, Gabon
East sub-Saharan Africa Countries with no data, comprising 100% of the regional population: Burundi, Comoros, Djibouti, Eritrea, Ethiopia, Kenya, Madagascar, Malawi, Mozambique, Rwanda, Somalia, Sudan, Uganda, United Republic of Tanzania, Zambia
West sub-Saharan Africa Countries with no data, comprising 100% of the regional population: Benin, Burkina Faso, Cameroon, Cape Verde, Chad, Côte d’Ivoire, Gambia, Ghana, Guinea, Guinea-Bissau, Liberia, Mali, Mauritania, Niger, Nigeria, Sao Tome and Principe, Senegal, Sierra Leone, Togo

ICD, International classification of diseases and related health problems; WHO, World Health Organization.

a Countries were grouped into the 21 global regions defined by the 2005 Global Burden of Diseases, Injuries and Risk Factors Study.10

b Only WHO member countries (listed at: http://www.who.int/countries) for which data were available from after 2000 were included.

c Any year in which a country reported data using the ICD-10 basic tabulation list was excluded. Since all ICD-9 data in the WHO mortality database were coded using the basic tabulation list, years reported in this way were generally not included. However, in a few instances, detailed ICD-9 data were available from WHO, enabling the relevant countries to be included. Countries that were excluded because a basic tabulation list was used were: Central Asia: Armenia, Azerbaijan, Kazakhstan, Mongolia, Tajikistan and Turkmenistan; East Asia: China; South Asia: Pakistan; South-East Asia: Malaysia, Philippines, Seychelles and Sri Lanka; Caribbean: Jamaica; Central Europe: Albania, Bosnia and Herzegovina and Bulgaria; Eastern Europe: Belarus, Russian Federation and Ukraine; Western Europe: Monaco and Switzerland; Central Latin America: Honduras; North Africa and the Middle East: Islamic Republic of Iran, Syrian Arab Republic and Turkey; and Oceania: Papua New Guinea.

d For example, after applying exclusion criteria, 2007 was the most recent year in which death registration data for Japan were available from the WHO mortality database and 13 years of data were available.

e China and India have sample registration systems that report the cause of death in some regions.

While historical death registration data were available for over a decade for many high-income countries, the most recent data for many of these countries dated from before 2005 (Table 3), which suggests that there were delays in reporting to WHO. Although low- and middle- income countries had been reporting data for a shorter time, 5 years of recent data were available for many. It should be noted that all of the ICD-9 data in the WHO mortality database were coded using the ICD-9 basic tabulation list, which limits the length of the historical record in these cases.

Table 3. Completeness of national death registration, the number of deaths due to different causes and the proportion of deaths assigned to various partially specified causes for selected countries included in the WHO mortality database, 2000–2007a.

Region,b country and year of most recent data
Asia Pacific, high-income countries Central Asia East Asia South-East Asia Australasia Caribbean Central and Eastern Europe Western Europe Latin America Northern Africa and the Middle East North America, high-income countries Southern sub-Saharan Africa
Japan Uzbekistan China, Hong Kong SAR Thailand Australia Cuba Poland Germany Brazil Egypt USA South Africa
2007 2005 2007 2002 2004 2006 2006 2006 2005 2000 2005 2005
Completeness of death registration High High High High High High High High Medium High High Medium
All-cause deaths, No. 1 083 796 140 585 38 678 380 364 132 314 84 824 368 285 830 227 1 006 827 382 138 2 448 017 591 213
   % of all-cause deaths ascribed to an unknown cause (ICD-10 codes: R95–R99) 0 1 1 14 1 1 4 2 9 1 1 11
Injury deaths, No. 75 380 10 142 2 150 42 803 7 970 7 047 25 363 33 024 127 608 16 709 176 406 53 124
   % of injury deaths ascribed to unspecified mechanism and intent 0 0 0 0 0 0 0 0 0 0 0 0
   % injury deaths ascribed to undetermined intent 3 13 6 24 1 4 10 7 9 42 3 66
Deaths due to unintentional injury, No. 41 937 6 356 827 24 117 5 603 4 670 16 134 19 993 59 519 9 424 120 462 12 853
   % of unintentional injury deaths ascribed to an unspecified unintentional injury 7 11 11 13 18 0 5 5 4 0 5 19
Deaths due to transport injury, No. 9 968 2 395 197 13 389 1 687 1 315 5 959 5 657 36 592 5 446 48 047 5 454
   % of transport injury deaths ascribed to unspecified transport injury 1 3 1 0 0 0 3 0 1 6 0 0
Deaths due to road injury, No. 9 434 2 277 175 13 251 1 582 1 255 5 456 5 409 35 736 4 381 45 812 5 354
   % of road injury deaths ascribed to unspecified unintentional road injury 4 7 0 39 7 2 11 28 26 1 25 87
   % of road injury deaths of vehicle occupants ascribed to unspecified unintentional road injury not including pedestrian or bicyclist 6 0 0 0 1 2 0 0 2 45 16 10
Deaths due to non-transport injury, No. 29 205 3 237 538 7 601 2 921 3 343 9 446 13 305 20 477 3 976 65 864 4 911
   % of non-transport injury deaths ascribed to unspecified unintentional non-transport injury 5 0 0 0 2 21 0 0 0 4 1 0
Deaths due to intentional injury, No. 31 159 1 959 1 185 8 328 2 278 2 083 6 603 10 730 56 701 315 51 202 5 435
Deaths due to interpersonal injury, No. 600 735 36 3 402 162 684 558 454 47 590 50 18 124 4 950
   % of interpersonal injury deaths ascribed to an unspecified mechanism 6 14 6 19 11 3 5 7 6 4 11 11
Deaths due to self-inflicted injury, No. 30 557 1 221 1 149 4 905 2 114 1 398 6 045 10 270 8 552 49 32 637 462
   % of self-inflicted injury deaths ascribed to an unspecified mechanism 0 4 0 8 0 0 0 2 4 4 1 5
Deaths due to legal intervention, No. 1 2 0 21 2 1 0 2 559 216 414 17
   % of legal intervention deaths ascribed to an unspecified mechanism 0 0 0 0 0 0 0 0 1 0 2 0
Deaths due to collective violence, No. 1 1 0 0 0 0 0 4 0 0 27 6

ICD, International classification of diseases and related health problems; SAR, Special Administrative Region; USA, United States of America; WHO, World Health Organization.

a Boldfaced table entries highlight instances where the percentage of injury deaths ascribed to a partially specified cause exceeds 20%, which is the upper limit for describing the data quality as high.

b Countries were grouped into the 21 global regions defined by the 2005 Global Burden of Diseases, Injuries and Risk Factors Study.10 The most populous country in each region from which data were analysed is shown. However, only one country is listed from the four Latin America regions and one from central and eastern Europe combined. The figures for all 83 countries analysed in the study are included in Appendix A (available at: http://www.globalburdenofinjuries.org/gimd/Quality_Global_Injury_Mortality_Data.pdf).

Completeness of registration

Of the 83 countries analysed, completeness was high (i.e. > 80%) in 62, medium (i.e. 60–80%) in 9, low (< 60%) in 5, and could not be assessed in the 7 for which no estimate of all-cause deaths was available from the United Nations Population Division. Table 3 lists the completeness of national death registration and the proportion of deaths assigned to various partially specified causes for selected countries. The figures for the remaining countries are listed in Appendix A (available at: http://www.globalburdenofinjuries.org/gimd/Quality_Global_Injury_Mortality_Data.pdf).

Data quality

Use of the broadest unspecified cause-of-death category, i.e. unknown cause of death (ICD-10 codes: R95–R99), was relatively rare. Only Haiti assigned more than 20% of all-cause deaths to this category. However, the use of codes for undetermined intent (ICD-10 codes: Y10–Y34, Y87.2) was common, with 18 countries, including one high-income country (i.e. Singapore), classifying more than 20% of injury deaths as due to undetermined intent. Two of the three countries from North Africa and the Middle East (i.e. Bahrain and Egypt) placed over one-third of all injury deaths in this category. The other countries with an exceptionally high number of deaths in this category included: Azerbaijan (83%), the Dominican Republic (45%), Egypt (42%), Guatemala (37%), Maldives (98%), Suriname (35%) and South Africa (66%). In contrast, the number of deaths classified as being due to an unspecified injury mechanism with undetermined intent (ICD-10 code: Y89.9) was negligible in all countries.

With regard to unintentional injuries, many countries coded a large number of deaths using the broadest unspecified mechanism category: unspecified unintentional injury (ICD-10 code: X59). In 15 countries, over half of which were in Western Europe, over 20% of unintentional injury deaths were allocated this code. The proportion of deaths coded to the unspecified non-transport injury subcategory of unspecified unintentional non-transport injury (ICD-10 code: Y86) was negligible in all countries, with the notable exception of Cuba.

With regard to transport deaths, only Georgia (46%) and Serbia (22%) allocated more than 20% of deaths to the broadest unspecified category: unspecified unintentional transport injury (ICD-10 codes: V99, Y85.9). However, many countries coded a large number of deaths due to road injury using the broadest unspecified category: unspecified unintentional road injury (ICD-10 codes: V89, Y85.0). In total, 40 countries used this code for more than 20% of road deaths. Many were high-income countries, including two in North America (i.e. Canada and the USA) and six in Western Europe, two of which (i.e. France and Portugal) allocated over 80% of road deaths to this category. The other partly specified subcategory of road injury, unspecified road injury not including a pedestrian or bicyclist (ICD-10 codes: V87–V88), was used less often. Only seven countries used this category for more than 20% of vehicle occupant deaths. Three of these (i.e. Greece, Ireland and San Marino) used ICD-9, which does not differentiate between different types of vehicle occupant.

With regard to suicide, the mechanism of death was usually specified. With the exception of Georgia, Haiti and Saint Lucia, no country attributed more than 20% of suicide deaths to an unspecified mechanism. However, the mechanism of homicide deaths was much less likely to be specified. In 13 countries, the mechanism was not specified for more than 20% of homicides. These countries included Portugal (27%) and Spain (22%) in Western Europe and, notably, Israel (43%). The mechanism of deaths classified as being due to a legal intervention was always specified. In no country, were more than 3% of these deaths attributed to an unspecified mechanism.

In general there was considerable heterogeneity between countries in the use of unspecified codes. While Australia and the United Kingdom of Great Britain and Northern Ireland classified a large proportion (i.e. 18% and 24%, respectively) of injury deaths as due to unspecified unintentional injury (ICD-10 code: X59), far fewer deaths were coded in this way in the USA (5%). On the other hand, 12% of all injury deaths were coded as due to undetermined intent (ICD-10 codes: Y10–Y34, Y87.2) in the United Kingdom, while the proportions were much smaller in Australia and the USA (1% and 3%, respectively).

Overall, only 20 countries did not allocate more than 20% of deaths to any partially specified category (Table 4). However, since the use of most partially specified categories influences data on only certain external causes of death, the number of countries whose data can be used to provide reliable estimates of deaths due to a particular external cause may be much larger than 20. For example, Table 4 lists 47 countries for which reliable estimates of road injury deaths were available and 60 for which reliable estimates of death due to suicide or homicide were available.

Table 4. Countries whose death registration data can be used to derive reliablea national estimates of deaths due to all external causes of injury, road injury, or suicide or homicide.

Regionb Country
Reliable estimates of deaths due to all external causes of injury (n = 20) Reliable estimates of deaths due to road injury (n = 47) Reliable estimates of deaths due to suicide or homicide (n = 60)
Asia Pacific, high-income countries Japan, Republic of Korea Japan, Republic of Korea Japan, Republic of Korea
Central Asia Uzbekistan Kyrgyzstan, Uzbekistan Kyrgyzstan, Uzbekistan
East Asia China, Hong Kong SAR China, Hong Kong SAR China, Hong Kong SAR
South-East Asia Mauritius Mauritius
Australasia Australia, New Zealand Australia, New Zealand Australia, New Zealand
Caribbean Barbados, Trinidad and Tobago Bahamas, Barbados, Belize, Cuba, Guyana, Saint Lucia, Trinidad and Tobago Bahamas, Barbados, Belize, Cuba, Guyana, Martinique, Saint Lucia, Trinidad and Tobago
Central Europe Hungary, Poland, Slovakia, Slovenia Croatia, Czech Republic, Hungary, Poland, Romania, Slovakia, Slovenia Croatia, Czech Republic, Hungary, Poland, Romania, Slovakia, Slovenia
Eastern Europe Estonia, Lithuania Estonia, Latvia, Lithuania, the Republic of Moldova Estonia, Latvia, Lithuania, the Republic of Moldova
Western Europe Finland, Iceland, Ireland, Luxembourg, Malta Austria, Finland, Germany, Greece, Iceland, Ireland, Luxembourg, Malta, Portugal, Spain Austria, Cyprus, Denmark, Finland, France, Germany, Greece, Iceland, Ireland, Israel, Italy, Luxembourg, Malta, Netherlands, Norway, Portugal, Spain, Sweden, United Kingdom
Latin America – Andean countries Ecuador
Central Latin America Panama Colombia, Costa Rica, El Salvador, Mexico, Panama Colombia, Costa Rica, El Salvador, Mexico, Panama
Southern Latin America Chile Argentina, Chile, Uruguay
Tropical Latin America Brazil, Paraguay Brazil, Paraguay
North Africa and the Middle East Kuwait Kuwait
North America, high-income countries Canada, United States of America Canada, United States of America

SAR, Special Administrative Region.

a Data on a particular external cause of death were rated as reliable if no more than 20% of deaths due to that external cause were attributed to any partially specified category. For example, deaths due to road injury can be reliably estimated if no more than 20% of deaths were attributed to the following categories: unknown cause of death (International classification of diseases and related health problems, 10th revision codes: R95–R99); injury death of unspecified mechanism; injury death of undetermined intent; death due to unintentional injury of unspecified mechanism; and death due to unintentional transport injury of unspecified mechanism. Similarly, deaths due to suicide or homicide can be reliably estimated if no more than 20% of deaths were attributed to the following categories: unknown cause of death (International classification of diseases and related health problems, 10th revision codes: R95–R99); injury death of unspecified mechanism; and injury death of undetermined intent.

b Countries were grouped into the 21 global regions defined by the 2005 Global Burden of Diseases, Injuries and Risk Factors Study.10

Discussion

Previous work on national and global mortality patterns has not paid sufficient attention to injuries. We undertook this analysis because the only other assessment of the quality of global cause-of-death data7 did not consider the use of the most common injury dump codes. Furthermore, the external causes of injuries are often poorly categorized in many administrative data systems. For instance, even in high-income countries with an extensive history of disease surveillance, hospital administration records commonly omit the external cause of an injury.1113 Similarly, in an unpublished analysis of mortality surveillance data based on verbal autopsy, which is the only source of mortality data in many information-poor settings, we found that often only the nature of the injury was reported for injury deaths. This is a serious shortcoming that will hamper attempts to develop injury prevention strategies since reliable estimates of the incidence of external causes of injuries are needed.14,15

The inadequate classification of injuries by ICD basic tabulation lists is another reason why injury deaths have not been fully considered. These summary lists do not provide codes for the mechanism of a suicide or homicide. Thus, the incidence of many important mechanisms of injuries (e.g. firearm injury, poisoning and burn injury) cannot be determined. In addition, the summary lists pose a more substantial problem for assessing mortality due to specific causes of injury. Usually the key injury dump codes identified in our analysis (e.g. ICD-10 code: X59) are grouped together with other specified mechanisms. Without access to data on these injury dump codes, the quality of the data overall cannot be assessed and injury mortality cannot be reliably estimated.

Ultimately, the purpose of this analysis was to identify those countries where the incidence of death due to injury can be reliably estimated. In the absence of empirical evidence to support a more nuanced characterization of quality, we adopted a maximum of 20% for each partially specified category for the cause of death to define high-quality data. While this threshold is to some extent arbitrary, it is based on the understanding that, when a large number of deaths have been allocated to partially specified categories, reapportioning deaths to specified categories can introduce substantial biases. Nevertheless, we showed that these categories contain a hierarchy of information content (i.e. they are partially specified) that should be harnessed fully to derive estimates of the incidence of death due to injury. Thus, although only 20 countries had high-quality data on all quality indicators, many more had high-quality data for specific external causes such as road injury, suicide and homicide.

The considerable heterogeneity between countries in the use of partially specified codes shows that they differ in coding practices. An understanding of those differences may enable us to identify biases arising from the dump codes used in specific countries and to derive appropriate reclassification rules for these deaths. There may also be commonalities in coding practices across countries that could help explain, for instance, why death registers in most countries tend to report the mechanism of suicides but not the mechanism of homicides.

In many countries, vital registration is the only comprehensive source of data for estimating mortality due to specific causes. Consequently, it has been proposed that national data should be validated and data quality should be improved, and this has already been done in several settings.1618 Although we focused on injury deaths, the standardized method for assessing data quality we used could be implemented by national agencies as part of their routine quality assurance practices. Temporal changes in data quality could be evaluated and one country’s data could be compared with those from other countries.

An important finding of our analysis is that reliable national death registration data were available for less than 30% of the global population, which means that alternative data sources must be used for estimating global injury mortality. The two most populous countries in the world, India and China, do not have reliable national death registration systems though they do have sample registration systems19 that may be useful for deriving estimates of death due to injury. Similarly, at present there are no national death registration systems in most of Africa and such systems are unlikely to become a reliable source of data for decades. Nevertheless, even in these information-poor settings there are several alternative data sources that can be used to estimate injury mortality. Notably these include demographic surveillance sites,20 mortuaries,21,22 national censuses containing information on the cause of death,23 and national health surveys that report the details of sibling mortality.24 Analytical methods that can derive national estimates of injury mortality from multiple data sources are urgently needed.

Our evaluation of the availability and quality of global death registration data has several limitations. First, we considered only the data available from the WHO mortality database, supplemented by additional data from a few countries. While this data set is the single largest global death registration repository, there are many countries that collect death registration data but do not report to WHO. It is also likely that more recent data are available from the national vital statistics agencies of many countries included in the WHO database. Second, our judgment of data quality was based on the proportion of deaths that was assigned to partially specified categories. However, the misclassification of deaths was not considered. For instance, it is likely that some deaths due to suicide were coded as due to an unintentional or undetermined cause because of the stigma associated with suicide, and other deaths may have been similarly coded because of medico-legal considerations associated with intentional death. Moreover, these misclassifications may vary substantially between countries. Misclassification could have significant impact on the accuracy of injury mortality estimates derived from death registration data.

Despite these shortcomings, this analysis is a step towards making global injury data comparable across countries. The next step in this process is to develop methods for processing death registration data sets such that reasonable estimates of cause-specific injury mortality can be derived. This would lead to the construction of an international database of injury deaths that could provide useful insights into the structural causes of variations in the incidence of injury mortality between countries. With access to such a database, the international injury research community could learn from the experiences of different countries and could identify the social, political and environmental prerequisites of safe and sustainable living conditions.

Funding:

No member of the GBD Injury Expert Group derived salary support from the Global Burden of Disease project. However, several members have ongoing funded research in closely associated areas. Kavi Bhalla and Saeid Shahraz are supported by a grant from the World Bank Global Road Safety Facility, but this funder played no role in the study design, data analysis, decision to publish or preparation of this manuscript.

Competing interests:

None declared.

References

  • 1.Murray CJL, Lopez AD. The global burden of disease: a comprehensive assessment of mortality and disability from diseases, injuries, and risk factors in 1990 and projected to 2020. Cambridge: Harvard University Press; 1996. [Google Scholar]
  • 2.Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med. 2006;3:e442. doi: 10.1371/journal.pmed.0030442. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.World Health Organization. The global burden of disease: 2004 update. Geneva: World Health Organization; 2008. [Google Scholar]
  • 4.Murray CJ, Lopez AD, Black R, Mathers CD, Shibuya K, Ezzati M, et al. Global burden of disease 2005: call for collaborators. Lancet. 2007;370:109–10. doi: 10.1016/S0140-6736(07)61064-2. [DOI] [PubMed] [Google Scholar]
  • 5.Bhalla K, Harrison J, Abraham J, Borse NN, Lyons R, Boufous S, et al. Global Burden of Disease Injury Expert Group Data sources for improving estimates of the global burden of injuries: call for contributors. PLoS Med. 2009;6:e1. doi: 10.1371/journal.pmed.1000001. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 6.WHO mortality database. Geneva: World Health Organization; 2008. Available from: http://www.who.int/healthinfo/statistics/mortdata [accessed 4 June 2010].
  • 7.Mathers CD, Fat DM, Inoue M, Rao C, Lopez AD. Counting the dead and what they died from: an assessment of the global status of cause of death data. Bull World Health Organ. 2005;83:171–7. [PMC free article] [PubMed] [Google Scholar]
  • 8.World Health Organization. International statistical classification of diseases and related health problems. Geneva: World Health Organization; 1992. [Google Scholar]
  • 9.World population prospects: the 2002 revision. New York: United Nations Population Division; 2003. Available from: http://esa.un.org/unpp [accessed 4 June 2010].
  • 10.Global Burden of Disease Injury Expert Group [Internet site]. Boston: Global Burden of Disease Injury Expert Group; 2009. Available from: http://sites.google.com/site/gbdinjuryexpertgroup [accessed 4 June 2010].
  • 11.Finkelstein EA, Corso PS, Miller TR. The incidence and economic burden of injuries in the United States. New York: Oxford University Press; 2006. [Google Scholar]
  • 12.Conner KR, Langley J, Tomaszewski KJ, Conwell Y. Injury hospitalization and risks for subsequent self-injury and suicide: a national study from New Zealand. Am J Public Health. 2003;93:1128–31. doi: 10.2105/AJPH.93.7.1128. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 13.Bhalla K, Shahraz S, Naghavi M, Lozano R, Murray C. Estimating the distribution of external causes in hospital data from injury diagnosis. Accid Anal Prev. 2008;40:1822–9. doi: 10.1016/j.aap.2008.07.002. [DOI] [PubMed] [Google Scholar]
  • 14.Sniezek JE, Finklea JF, Graitcer PL. Injury coding and hospital discharge data. JAMA. 1989;262:2270–2. doi: 10.1001/jama.262.16.2270. [DOI] [PubMed] [Google Scholar]
  • 15.Lawrence BA, Miller TR, Weiss HB, Spicer RS. Issues in using state hospital discharge data in injury control research and surveillance. Accid Anal Prev. 2007;39:319–25. doi: 10.1016/j.aap.2006.08.001. [DOI] [PubMed] [Google Scholar]
  • 16.Rosenberg HM. Improving cause-of-death statistics. Am J Public Health. 1989;79:563–4. doi: 10.2105/AJPH.79.5.563. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 17.Sirken MG, Rosenberg HM, Chevarley FM, Curtin LR. The quality of cause-of-death statistics. Am J Public Health. 1987;77:137–9. doi: 10.2105/AJPH.77.2.137. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 18.McKenzie K, Chen L, Walker SM. Correlates of undefined cause of injury coded mortality data in Australia. HIM J. 2009;38:8–14. doi: 10.1177/183335830903800102. [DOI] [PubMed] [Google Scholar]
  • 19.Setel PW, Macfarlane SB, Szreter S, Mikkelsen L, Jha P, Stout S, et al. Monitoring of Vital Events A scandal of invisibility: making everyone count by counting everyone. Lancet. 2007;370:1569–77. doi: 10.1016/S0140-6736(07)61307-5. [DOI] [PubMed] [Google Scholar]
  • 20.Adjuik M, Smith T, Clark S, Todd J, Garrib A, Kinfu Y, et al. Cause-specific mortality rates in sub-Saharan Africa and Bangladesh. Bull World Health Organ. 2006;84:181–8. doi: 10.2471/BLT.05.026492. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 21.Butchart A, Peden M, Matzopoulos R, Phillips R, Burrows S, Bhagwandin N, et al. The South African National Non-Natural Mortality Surveillance System–rationale, pilot results and evaluation. S Afr Med J. 2001;91:408–17. [PubMed] [Google Scholar]
  • 22.Wolde A, Abdella K, Ahmed E, Tsegaye F, Babaniyi OA, Kobusingye O, et al. Pattern of injuries in Addis Ababa, Ethiopia: a one-year descriptive study. East Centr Afr J Surg. 2008;13:14–22. [Google Scholar]
  • 23.Setel PW, Sankoh O, Rao C, Velkoff VA, Mathers C, Gonghuan Y, et al. Sample registration of vital events with verbal autopsy: a renewed commitment to measuring and monitoring vital statistics. Bull World Health Organ. 2005;83:611–7. [PMC free article] [PubMed] [Google Scholar]
  • 24.Gakidou E, King G. Death by survey: estimating adult mortality without selection bias from sibling survival data. Demography. 2006;43:569–85. doi: 10.1353/dem.2006.0024. [DOI] [PubMed] [Google Scholar]

Articles from Bulletin of the World Health Organization are provided here courtesy of World Health Organization

RESOURCES