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. 1968 Feb;47(2):242–248. doi: 10.1172/JCI105720

The renal tubular handling of aldosterone and its acid-labile conjugate

Murphy T Scurry 1, Leroy Shear 1, Kevin G Barry 1
PMCID: PMC297166  PMID: 12066773

Abstract

Stop-flow studies using infusions of aldosterone-3H or its 3H acid-labile conjugate were done on five rhesus monkeys. The aldosterone-3H urine-to-plasma (U/P) ratio decreased in the same distal urine samples as sodium. The 3H acid-labile conjugate U/P-to-inulin U/P ratio increased in the more proximal samples either with conjugate formed endogenously during aldosterone-3H infusions or with labeled conjugate infused alone. Aldosterone reabsorption occurred at a distal site in the renal tubule, and secretion of its acid-labile conjugate occurred at a proximal site.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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