Abstract
Sixty patients with chloroquine induced psychiatric complications are reported in the present series. Psychosis was the most common complication followed by anxiety state and seizures. The maximum number of patients were between the ages of 6 and 10 years and females (70.0%) outnumbered the males (30.0%). Headache and sleeplessness were found to be more common amongpatients developing psychiatric complications of chloroquine. The symptoms disappeared within 2 to 21 days after the discontinuation of chloroquine.
Keywords: chloroquine, psychoses, neuroses, seizures
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- BURRELL Z. L., Jr, MARTINEZ A. C. Chloroquine and hydroxychloroquine in the treatment of cardiac arrhythmias. N Engl J Med. 1958 Apr 17;258(16):798–800. doi: 10.1056/NEJM195804172581608. [DOI] [PubMed] [Google Scholar]
- Bhatia M. S. Chloroquine-induced psychiatric complications. Br J Psychiatry. 1991 Nov;159:735–735. doi: 10.1192/bjp.159.5.735. [DOI] [PubMed] [Google Scholar]
- Bhatia M. S., Singhal P. K., Dhar N. K. Chloroquine induced psychosis. Indian Pediatr. 1988 Mar;25(3):258–262. [PubMed] [Google Scholar]
- Garg P., Mody P., Lall K. B. Toxic psychosis due to chloroquine--not uncommon in children. Clin Pediatr (Phila) 1990 Aug;29(8):448–450. doi: 10.1177/000992289002900806. [DOI] [PubMed] [Google Scholar]
- Good M. I., Shader R. I. Behavioral toxicity and equivocal suicide associated with chloroquine and its derivatives. Am J Psychiatry. 1977 Jul;134(7):798–601. doi: 10.1176/ajp.134.7.798. [DOI] [PubMed] [Google Scholar]
- KIEL F. W. CHLOROQUINE SUICIDE. JAMA. 1964 Oct 26;190:398–400. doi: 10.1001/jama.1964.03070170139030. [DOI] [PubMed] [Google Scholar]