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. 1968 Sep;47(9):2125–2132. doi: 10.1172/JCI105898

Regional distribution of acid mucopolysaccharides in the kidney

C W Castor 1, J A Greene 1
PMCID: PMC297373  PMID: 4233982

Abstract

Kidneys from 20 dogs were dissected into cortical and medullary components and analysed for acid mucopolysaccharide content. Heparitin sulfate accounted for approximately 80% of cortical acid mucopolysaccharide, 10% was chondroitin sulfate B, and 10% was low molecular weight hyaluronic acid. Medullary tissue exhibited a 4- to 5-fold higher concentration of acid mucopolysaccharide than did cortical tissue, and the dominant compound was moderately highly polymerized hyaluronic acid. While chondroitin sulfates A and (or) C were not detected in this study, the presence of minor amounts of these substances could not be excluded. A model experiment indicated that hyaluronic acid retards sodium diffusion, apparently due to its viscous properties rather than its electronegativity.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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