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. 1989 Aug;86(16):6293–6296. doi: 10.1073/pnas.86.16.6293

A third T-cell receptor beta-chain variable region gene encodes reactivity to Mls-1a gene products.

M P Happ 1, D L Woodland 1, E Palmer 1
PMCID: PMC297824  PMID: 2474831

Abstract

Using a quantitative RNA hybridization method, we have identified a third murine T-cell receptor beta-chain variable (V) region gene, V beta 9, that engenders recognition of Mls-1a gene products. V beta 9-expressing T cells are clonally deleted from the periphery of mice that carry the Mls-1a allele, and the fine specificity of V beta 9+ hybridomas suggests that V beta 6-, V beta 8.1-, and V beta 9-encoded T-cell receptors may recognize a similar antigenic epitope. Comparison of these three protein sequences identifies two residues that may be important in determining this recognition specificity.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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