Table 1.

Changes in neurologic disability of animals with ischemia on day 1 and day 3 after transient MCA occlusion.

Treatment Group	Limb Placement						Beam Walking						Grid Walking
	Day 1			Day 3			Day 1			Day 3			Day 1			Day 3
	Med	25%	75%	Med	25%	75%	Med	25%	75%	Med	25%	75%	Med	25%	75%	Med	25%	75%
Normal (No Hypoxia)	2.0*	2.0	2.0	2.0*	2.0	2.0	1.0*	1.0	1.0	1.0*	1.0	1.3	0.5*	0.0	1.3	0.5*	0.0	1.3
No Treatment	0.0	0.0	0.0	1.0	0.8	1.0	5.0	4.8	5.0	4.5	4.0	5.0	47	46	48	45	42	47
Xe-Solution Treatment	1.0*	1.0	1.0	2.0*	2.0	2.0	2.5*	2.0	3.0	2.0*	2.0	2.0	5.0*	4.8	6.3	3.0*	2.8	3.3
Xe-ELIP Treatment	1.0*	1.0	1.0	2.0*	2.0	2.0	4.0++	4.0	4.0	3.0**	3.0	4.0	10*	10	12	7.5*	6.0	8.3
Xe-ELIP Treatment + US Exposure	1.5*	1.0	2.0	2.0*	2.0	2.0	3.5+	3.0	4.0	2.0*	2.0	3.0	8.0*	7.8	8.8	4.0*	3.0	5.3

Data are presented as median and quartiles, US – ultrasound.

^*p<0.001,

^**p=0.002,

⁺p=0.01,

⁺⁺p=0.03 vs. No treatment group, n=8.

Scores in the limb placement: 0 – no response; 1 – response was sluggish or delayed; 2 response was rapid and fully executed.

Scores in the beam walking: 0 – traversed the beam with no foot slip; 1 – traversed with grasping of the lateral side of the beam; 2 – showed difficulty crawling across the beam but able to traverse; 3 – required a more than 10 seconds to traverse the beam due to difficulty in walking; 4 – unable to traverse the beam; 5 – unable to move the body or any limb on the beam; 6 – unable to stay on the beam for more than 10 seconds.

Scores in the grid walking: Total number of foot fault errors.