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Indian Journal of Psychiatry logoLink to Indian Journal of Psychiatry
. 1992 Jul-Sep;34(3):264–272.

MULTIPLE ENDOCRINE RESPONSES TO CLONIDINE IN OBSESSIVE COMPULSIVE DISSORDER

Sumant Khanna 1,✉, PL Reddy 2, MN Subhash 2, BS Sridhara Rama Rao 2, SM Channabasavanna 1
PMCID: PMC2982080  PMID: 21776130

Abstract

Seventy two subjects with OCD were compared with 18 normal healthy volunteers on multiple neuroendocrine responses to clonidine. Significant heterogeneity in OCD was observed in responses of growth hormone. There was also significant disturbances in Cortisol and ACTH release. An interactional model for noradrenergic and serotonergic dysfunction in OCD is discussed.

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Selected References

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