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Effect of different NNRTIs on the frequency of RT template switching by wild-type and K103N mutant RTs (A) The effect of NNRTI treatment on the template switching frequency by wild type HIV-1 RT is dependent on the affinity of NNRTI to the RT. (B) Effect of decreased affinity of EFV to the drug resistant K103N mutant RT on the template switching frequency. Figure represents data described in [86].
