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. 1989 Nov;86(22):8882–8886. doi: 10.1073/pnas.86.22.8882

The unexpected antitermination of gyrA-directed transcripts is enhanced by DNA relaxation.

M Carty 1, R Menzel 1
PMCID: PMC298394  PMID: 2554334

Abstract

We show that transcription originating at the gyrA promoter of Escherichia coli is less subject to termination at the lambda Toop terminator (22% read-through) than is transcription originating from either the galOP (1% read-through) or topA (3% read-through) control regions. Furthermore, termination of the gyrA transcripts decreases (60% read-through) upon relaxation of the template DNA. We believe that events related to stimulation of transcription at the gyrA promoter by DNA relaxation are responsible for the enhanced terminator read-through.

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Selected References

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