Table 1.
Patient Characteristics
| Patient No. |
Sex | Age, y, mo |
Disease Status | Disease Sites | Previous Treatment | Other Medical Problems |
|---|---|---|---|---|---|---|
| 1 | F | 18, 7 | Recurrence 2 | L2 vertebral body, left lung | Cisplatin/doxorubicin/MTX | |
| 2 | M | 17, 6 | Primary refractory | Lungs, inguinal lymph nodes | Cisplatin/doxorubicin/MTX/VP-16/ifosfamide | |
| 3 | M | 17, 3 | Refractory recurrence 2 | Sacrum | Cisplatin/doxorubicin/MTX/VP-16/ifosfamide; inhaled GM-CSF; gemcitabine/Taxotere; local XRT, topotecan; samarium-153/gemcitabine | Cardiomyopathy |
| 4 | F | 30, 9 | Recurrence 4 | Chest wall | Cisplatin/doxorubicin/MTX; gemcitabine/Taxotere; ifosfamide | |
| 5 | M | 20, 2 | Refractory recurrence 2 | Lungs, rib, shoulder | Cisplatin/doxorubicin/MTX/VP-16/ifosfamide; XRT; inhaled GM-CSF | |
| 6 | M | 15, 5 | Primary refractory | Ribs, spine, right knee | Cisplatin/doxorubicin/MTX/VP-16/ifosfamide | |
| 7 | M | 15, 5 | Primary refractory (secondary to XRT for medulloblastoma) | Temporal bone | Cisplatin/doxorubicin/VP-16/ifosfamide (history of XRT and chemotherapy for medulloblastoma) | |
| 8 | F | 14, 3 | Recurrence 3 | Left lung, skull, patella, pelvis | Cisplatin/doxorubicin/MTX/VP-16/ifosfamide | |
| 9 | F | 19, 3 | Recurrence 2 | Skull, ribs, right femur, abdomen | Cisplatin/doxorubicin/MTX/VP-16/ifosfamide; XRT; inhaled GM-CSF | |
| 10 | M | 21, 2 | Recurrence 2 | Right upper lobe of lung, L4 and S1 vertebral bodies, right ilium, retroperitoneal soft tissue | Cisplatin/doxorubicin/MTX/VP-16/ifosfamide; gemcitabine | Asthma |
| 11 | F | 25, 6 | Recurrence 1 | Lungs, inguinal nodes | Cisplatin/doxorubicin/MTX/VP-16/ifosfamide |
F indicates female; MTX, methotrexate; M, male; GM-CSF, granulocyte-macrophage colony-stimulating factor; XRT, external radiation therapy.