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. 1987 Nov;84(22):7987–7991. doi: 10.1073/pnas.84.22.7987

A short 5'-flanking DNA region is sufficient for developmentally correct expression of moth chorion genes in Drosophila.

S A Mitsialis 1, N Spoerel 1, M Leviten 1, F C Kafatos 1
PMCID: PMC299461  PMID: 3120180

Abstract

Fusions with the bacterial gene for chloramphenicol acetyltransferase followed by P-element-mediated germ-line transformation in Drosophila have permitted localization of the DNA sequence that confers a high degree of developmental specificity on a pair of silkmoth eggshell (chorion) genes. The short, 272-base-pair, 5'-flanking region shared by the divergently transcribed genes is sufficient for developmentally appropriate expression when placed upstream of the chloramphenicol acetyltransferase gene, in either orientation. A highly conserved motif within that region, TCACGT, is essential for chorion-specific expression.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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