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. 1964 Jun;51(6):1231–1238. doi: 10.1073/pnas.51.6.1231

THE ACYL CARRIER PROTEIN OF FATTY ACID SYNTHESIS: PURIFICATION, PHYSICAL PROPERTIES, AND SUBSTRATE BINDING SITE

Philip W Majerus 1, Alfred W Alberts 1, P Roy Vagelos 1
PMCID: PMC300242  PMID: 14215649

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BRODIE J. D., WASSON G. W., PORTER J. W. The formation of malonyl-enzyme and its conversion to fatty acids and beta-hydroxy, beta-methyl glutaryl coenzyme A. Biochem Biophys Res Commun. 1963 Jul 10;12:27–33. doi: 10.1016/0006-291x(63)90408-x. [DOI] [PubMed] [Google Scholar]
  2. BRODIE J. D., WASSON G., PORTER J. W. The participation of malonyl coenzyme A in the biosynthesis of mevalonic acid. J Biol Chem. 1963 Apr;238:1294–1301. [PubMed] [Google Scholar]
  3. ELLMAN G. L. Tissue sulfhydryl groups. Arch Biochem Biophys. 1959 May;82(1):70–77. doi: 10.1016/0003-9861(59)90090-6. [DOI] [PubMed] [Google Scholar]
  4. GOLDMAN P., ALBERTS A. W., VAGELOS P. R. THE CONDENSATION REACTION OF FATTY ACID SYNTHESIS.III. IDENTIFICATION OF THE PROTEIN-BOUND PRODUCT OF THE REACTION AND ITS CONVERSION TO LONG CHAIN FATTY ACIDS. J Biol Chem. 1963 Nov;238:3579–3583. [PubMed] [Google Scholar]
  5. GOLDMAN P., ALBERTS A. W., VAGELOS P. R. The condensation reaction of fatty acid biosynthesis. II. Requirement of the enzymes of the condensation reaction for fatty acid synthesis. J Biol Chem. 1963 Apr;238:1255–1261. [PubMed] [Google Scholar]
  6. GOLDMAN P., VAGELOS P. R. The formation of enzyme-bound acetoacetate and its conversion to long chain fatty acids. Biochem Biophys Res Commun. 1962 May 11;7:414–418. doi: 10.1016/0006-291x(62)90326-1. [DOI] [PubMed] [Google Scholar]
  7. KATZ A. M., DREYER W. J., ANFINSEN C. B. Peptide separation by two-dimensional chromatography and electrophoresis. J Biol Chem. 1959 Nov;234:2897–2900. [PubMed] [Google Scholar]
  8. LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
  9. LYNEN F. Biosynthesis of saturated fatty acids. Fed Proc. 1961 Dec;20:941–951. [PubMed] [Google Scholar]
  10. Lennarz W. J., Light R. J., Bloch K. A FATTY ACID SYNTHETASE FROM E. COLI. Proc Natl Acad Sci U S A. 1962 May;48(5):840–846. doi: 10.1073/pnas.48.5.840. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. MARTIN D. B., VAGELOS P. R. Evidence against free butyryl-CoA as an intermediate in long chain fatty acid biosynthesis. Biochem Biophys Res Commun. 1961 May 15;5:16–21. doi: 10.1016/0006-291x(61)90072-9. [DOI] [PubMed] [Google Scholar]

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