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. 1964 Aug;52(2):342–349. doi: 10.1073/pnas.52.2.342

CHARACTERIZATION OF THE LONG-ACTING THYROID STIMULATOR OF GRAVES' DISEASE*

Joseph C Meek 1,†, A Eric Jones 1, U J Lewis 1, W P VanderLaan 1
PMCID: PMC300282  PMID: 14206601

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BROWN D. M., LOWMAN J. T. THYROTOXICOSIS OCCURRING IN TWO PATIENTS ON PROLONGED HIGH DOSES OF STEROIDS. N Engl J Med. 1964 Feb 6;270:278–281. doi: 10.1056/NEJM196402062700604. [DOI] [PubMed] [Google Scholar]
  2. BUCKLEY C. E., 3rd, WHITNEY P. L., TANFORD C. THE UNFOLDING AND RENATURATION OF A SPECIFIC UNIVALENT ANTIBODY FRAGMENT. Proc Natl Acad Sci U S A. 1963 Nov;50:827–834. doi: 10.1073/pnas.50.5.827. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. COHEN S. PROPERTIES OF THE PEPTIDE CHAINS OF NORMAL AND PATHOLOGICAL HUMAN GAMMA GLOBULINS. Biochem J. 1963 Nov;89:334–341. doi: 10.1042/bj0890334. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. CRUMPTON M. J., WILKINSON J. M. AMINO ACID COMPOSITIONS OF HUMAN AND RABBIT GAMMA-GLOBULINS AND OF THE FRAGMENTS PRODUCED BY REDUCTION. Biochem J. 1963 Aug;88:228–234. doi: 10.1042/bj0880228. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. EDELMAN G. M., HEREMANS J. F., HEREMANS M. T., KUNKEL H. G. Immunological studies of human gamma-globulin. Relation of the precipitin lines of whole gamma-globulin to those of the fragments produced by papain. J Exp Med. 1960 Jul 1;112:203–223. doi: 10.1084/jem.112.1.203. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. FLEISCHMAN J. B., PAIN R. H., PORTER R. R. Reduction of gamma-globulins. Arch Biochem Biophys. 1962 Sep;Suppl 1:174–180. [PubMed] [Google Scholar]
  7. FLEISCHMAN J. B., PORTER R. R., PRESS E. M. THE ARRANGEMENT OF THE PEPTIDE CHAINS IN GAMMA-GLOBULIN. Biochem J. 1963 Aug;88:220–228. doi: 10.1042/bj0880220. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. MCKENZIE J. M. Fractionation of plasma containing the long acting thyroid stimulator. J Biol Chem. 1962 Nov;237:3571–3572. [PubMed] [Google Scholar]
  9. MCKENZIE J. M. Studies on the thyroid activator of hyperthyroidism. J Clin Endocrinol Metab. 1961 Jun;21:635–647. doi: 10.1210/jcem-21-6-635. [DOI] [PubMed] [Google Scholar]
  10. METZGER H., WOFSY L., SINGER S. J. THE PARTICIPATION OF A AND B POLYPEPTIDE CHAINS IN THE ACTIVE SITES OF ANTIBODY MOLECULES. Proc Natl Acad Sci U S A. 1964 Apr;51:612–618. doi: 10.1073/pnas.51.4.612. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. MUNRO D. S. Observations on the discharge of radio-iodine from the thyroid glands of mice injected with human sera. J Endocrinol. 1959 Oct;19:64–73. doi: 10.1677/joe.0.0190064. [DOI] [PubMed] [Google Scholar]
  12. McKENZIE J. M. Delayed thyroid response to serum from thyrotoxic patients. Endocrinology. 1958 Jun;62(6):865–868. doi: 10.1210/endo-62-6-865. [DOI] [PubMed] [Google Scholar]
  13. McKENZIE J. M. The bioassay of thyrotropin in serum. Endocrinology. 1958 Sep;63(3):372–382. doi: 10.1210/endo-63-3-372. [DOI] [PubMed] [Google Scholar]
  14. OLINS D. E., EDELMAN G. M. RECONSTITUTION OF 7S MOLECULES FROM L AND H POLYPEPTIDE CHAINS OF ANTIBODIES AND GAMMA-GLOBULINS. J Exp Med. 1964 May 1;119:789–815. doi: 10.1084/jem.119.5.789. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. PALMER J. L., MANDY W. J., NISONOFF A. Heterogeneity of rabbit antibody and its subunits. Proc Natl Acad Sci U S A. 1962 Jan 15;48:49–53. doi: 10.1073/pnas.48.1.49. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. PIMSTONE B. L., HOFFENBERG R., BLACK E. Parallel assays of thyrotrophin, long-acting thyroid stimulator and exophthalmos-producing substance in some endocrine disorders. J Clin Endocrinol Metab. 1963 Apr;23:336–345. doi: 10.1210/jcem-23-4-336. [DOI] [PubMed] [Google Scholar]
  17. PORTER R. R. The hydrolysis of rabbit y-globulin and antibodies with crystalline papain. Biochem J. 1959 Sep;73:119–126. doi: 10.1042/bj0730119. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. REISFELD R. A., LEWIS U. J., WILLIAMS D. E. Disk electrophoresis of basic proteins and peptides on polyacrylamide gels. Nature. 1962 Jul 21;195:281–283. doi: 10.1038/195281a0. [DOI] [PubMed] [Google Scholar]
  19. ROHOLT O., ONOUE K., PRESSMAN D. SPECIFIC COMBINATION OF H AND L CHAINS OF RABBIT GAMMA-GLOBULINS. Proc Natl Acad Sci U S A. 1964 Feb;51:173–178. doi: 10.1073/pnas.51.2.173. [DOI] [PMC free article] [PubMed] [Google Scholar]

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