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. 1964 Sep;52(3):716–721. doi: 10.1073/pnas.52.3.716

EVIDENCE FOR A FALSE NEUROCHEMICAL TRANSMITTER AS A MECHANISM FOR THE HYPOTENSIVE EFFECT OF MONOAMINE OXIDASE INHIBITORS

Irwin J Kopin 1, Josef E Fischer 1, Jose Musacchio 1, W Dale Horst 1
PMCID: PMC300335  PMID: 14212547

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BROWN G. L., GILLESPIE J. S. The output of sympathetic transmitter from the spleen of the cat. J Physiol. 1957 Aug 29;138(1):81–102. doi: 10.1113/jphysiol.1957.sp005839. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BURNSTOCK G., HOLMAN M. E. Spontaneous potential at sympathetic nerve endings in smooth muscle. J Physiol. 1962 Mar;160:446–460. doi: 10.1113/jphysiol.1962.sp006858. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. CARLSSON A., WALDECK B. BETA-HYDROXYLATION OF TYRAMINE IN VIVO. Acta Pharmacol Toxicol (Copenh) 1963;20:371–374. doi: 10.1111/j.1600-0773.1964.tb01759.x. [DOI] [PubMed] [Google Scholar]
  4. DAVEY M. J., FARMER J. B., REINERT H. The effects of nialamide on adrenergic functions. Br J Pharmacol Chemother. 1963 Feb;20:121–134. doi: 10.1111/j.1476-5381.1963.tb01303.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. DAY M. D., RAND M. J. A hypothesis for the mode of action of alpha-methyldopa in relieving hypertension. J Pharm Pharmacol. 1963 Apr;15:221–224. doi: 10.1111/j.2042-7158.1963.tb12778.x. [DOI] [PubMed] [Google Scholar]
  6. DAY M. D., RAND M. J. TACHYPHYLAXIS TO SOME SYMPATHOMIMETIC AMINES IN RELATION TO MONOAMINE OXIDASE. Br J Pharmacol Chemother. 1963 Aug;21:84–96. doi: 10.1111/j.1476-5381.1963.tb01504.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. FATT P., KATZ B. Spontaneous subthreshold activity at motor nerve endings. J Physiol. 1952 May;117(1):109–128. [PMC free article] [PubMed] [Google Scholar]
  8. FISCHER J. E., MUSACCHIO J., KOPIN I. J., AXELROD J. EFFECTS OF DENERVATION ON THE UPTAKE AND BETA-HYDROXYLATION OF TYRAMINE IN THE RAT SALIVARY GLAND. Life Sci. 1964 May;3:413–419. doi: 10.1016/0024-3205(64)90201-2. [DOI] [PubMed] [Google Scholar]
  9. KAKIMOTO Y., ARMSTRONG M. D. On the identification of octopamine in mammals. J Biol Chem. 1962 Feb;237:422–427. [PubMed] [Google Scholar]
  10. LANDS A. M., GRANT J. I. The vasopressor action and toxicity of cyclohexylethylamine derivatives. J Pharmacol Exp Ther. 1952 Nov;106(3):341–345. [PubMed] [Google Scholar]
  11. MUSCHOLL E., MAITRE L. RELEASE BY SYMPATHETIC STIMULATION OF ALPHA-METHYLNORADRENALINE STORED IN THE HEART AFTER ADMINISTRATION OF ALPHA-METHYLDOPA. Experientia. 1963 Dec 15;19:658–659. doi: 10.1007/BF02151307. [DOI] [PubMed] [Google Scholar]
  12. ORVIS H. H., TAMAGNA I. G., HORWITZ D., THOMAS R. Correlation of hypotensive effects and urinary tryptamine levels during pargyline therapy. Ann N Y Acad Sci. 1963 Jul 8;107:958–965. doi: 10.1111/j.1749-6632.1963.tb13339.x. [DOI] [PubMed] [Google Scholar]
  13. SJOERDSMA A., LOVENBERG W., OATES J. A., CROUT J. R., UDENFRIEND S. Alterations in the pattern of amine excretion in man produced by a monoamine oxidase inhibitor. Science. 1959 Jul 24;130(3369):225–225. doi: 10.1126/science.130.3369.225. [DOI] [PubMed] [Google Scholar]
  14. WEISSBACH H., LOVENBERG W., UDENFRIEND S. Enzymatic decarboxylation of alpha-methyl amino acids. Biochem Biophys Res Commun. 1960 Aug;3:225–227. doi: 10.1016/0006-291x(60)90228-x. [DOI] [PubMed] [Google Scholar]
  15. WOLFE D. E., POTTER L. T., RICHARDSON K. C., AXELROD J. Localizing tritiated norepinephrine in sympathetic axons by electron microscopic autoradiography. Science. 1962 Oct 19;138(3538):440–442. doi: 10.1126/science.138.3538.440. [DOI] [PubMed] [Google Scholar]

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