Skip to main content
NCBI home page
Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1964 Sep;52(3):796–804. doi: 10.1073/pnas.52.3.796

THE ENZYMATIC SYNTHESIS OF A CIRCULAR DNA-RNA HYBRID*

Alix Bassel 1, M Hayashi 1, S Spiegelman 1
PMCID: PMC300348  PMID: 14212559

Full text

PDF
796

Images in this article

800Image
on p.800
801Image
on p.801
801Image
on p.801

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BREMER H., KONRAD M. W. A COMPLEX OF ENZYMATICALLY SYNTHESIZED RNA AND TEMPLATE DNA. Proc Natl Acad Sci U S A. 1964 May;51:801–808. doi: 10.1073/pnas.51.5.801. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. CHAMBERLIN M., BALDWIN R. L., BERG P. AN ENZYMICALLY SYNTHESIZED RNA OF ALTERNATING BASE SEQUENCE: PHYSICAL AND CHEMICAL CHARACTERIZATION. J Mol Biol. 1963 Oct;7:334–349. doi: 10.1016/s0022-2836(63)80028-5. [DOI] [PubMed] [Google Scholar]
  3. CHAMBERLIN M., BERG P. Deoxyribo ucleic acid-directed synthesis of ribonucleic acid by an enzyme from Escherichia coli. Proc Natl Acad Sci U S A. 1962 Jan 15;48:81–94. doi: 10.1073/pnas.48.1.81. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. CHAMBERLIN M., BERG P. MECHANISM OF RNA POLYMERASE ACTION: FORMATION OF DNA-RNA HYBRIDS WITH SINGLE-STRANDED TEMPLATES. J Mol Biol. 1964 Feb;8:297–313. doi: 10.1016/s0022-2836(64)80139-x. [DOI] [PubMed] [Google Scholar]
  5. CHANDLER B., HAYASHI M., HAYASHI M. N., SPIEGELMAN S. CIRCULARITY OF THE REPLICATING FORM OF A SINGLE-STRANDED DNA VIRUS. Science. 1964 Jan 3;143(3601):47–49. doi: 10.1126/science.143.3601.47. [DOI] [PubMed] [Google Scholar]
  6. DOERFLER W., ZILLIG W., FUCHS E., ALBERS M. [Studies on the biosyhthesis of proteins. V. The function of nucleic acids in the incorporation of amino acids into proteins in a cell free system in Esherichia coli]. Hoppe Seylers Z Physiol Chem. 1962 Dec 15;330:96–123. doi: 10.1515/bchm2.1962.330.1.96. [DOI] [PubMed] [Google Scholar]
  7. DOI R. H., SPIEGELMAN S. Conservation of a viral RNA genome during replication and translation. Proc Natl Acad Sci U S A. 1963 Mar 15;49:353–360. doi: 10.1073/pnas.49.3.353. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. FIERS W., SINSHEIMER R. L. The structure of the DNA of bacteriophage phi-X174. I. The action of exopolynucleotidases. J Mol Biol. 1962 Oct;5:408–419. doi: 10.1016/s0022-2836(62)80029-1. [DOI] [PubMed] [Google Scholar]
  9. HARUNA I., NOZU K., OHTAKA Y., SPIEGELMAN S. AN RNA "REPLICASE" INDUCED BY AND SELECTIVE FOR A VIRAL RNA: ISOLATION AND PROPERTIES. Proc Natl Acad Sci U S A. 1963 Nov;50:905–911. doi: 10.1073/pnas.50.5.905. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. HAYASHI M., HAYASHI M. N., SPIEGELMAN S. DNA CIRCULARITY AND THE MECHANISM OF STRAND SELECTION IN THE GENERATION OF GENETIC MESSAGES. Proc Natl Acad Sci U S A. 1964 Feb;51:351–359. doi: 10.1073/pnas.51.2.351. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. HAYASHI M., HAYASHI M. N., SPIEGELMAN S. RESTRICTION OF IN VIVO GENETIC TRANSCRIPTION TO ONE OF THE COMPLEMENTARY STRANDS OF DNA. Proc Natl Acad Sci U S A. 1963 Oct;50:664–672. doi: 10.1073/pnas.50.4.664. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. HAYASHI M., HAYASHI M. N., SPIEGELMANS Replicating form of a single-stranded DNA virus: isolation and properties. Science. 1963 Jun 21;140(3573):1313–1316. doi: 10.1126/science.140.3573.1313. [DOI] [PubMed] [Google Scholar]
  13. KLEINSCHMIDT A. K., BURTON A., SINSHEIMER R. L. ELECTRON MICROSCOPY OF THE REPLICATIVE FORM OF THE DNA OF THE BACTERIOPHAGE PHI-X174. Science. 1963 Nov 15;142(3594):961–961. doi: 10.1126/science.142.3594.961. [DOI] [PubMed] [Google Scholar]
  14. KLEINSCHMIDT A. K., LANG D., JACHERTS D., ZAHN R. K. [Preparation and length measurements of the total desoxyribonucleic acid content of T2 bacteriophages]. Biochim Biophys Acta. 1962 Dec 31;61:857–864. [PubMed] [Google Scholar]
  15. KONRAD M. W., STENT G. S. ON "NATURAL" DNA-RNA COMPLEXES IN PHAGE-INFECTED E. COLI. Proc Natl Acad Sci U S A. 1964 Apr;51:647–653. doi: 10.1073/pnas.51.4.647. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. MEAD C. G. A DEOXYRIBONUCLEIC ACID-ASSOCIATED RIBONUCLEIC ACID FROM DROSOPHILA MELANOGASTER. J Biol Chem. 1964 Feb;239:550–554. [PubMed] [Google Scholar]
  17. SIBATANI A., DE KLOET S. R., ALLFREY V. G., MIRSKY A. E. Isolation of a nuclear RNA fraction resembling DNA in its base composition. Proc Natl Acad Sci U S A. 1962 Mar 15;48:471–477. doi: 10.1073/pnas.48.3.471. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. SIBATANI A., YAMANA K., KIMURA K., TAKAHASHI T. Fractionation of two metabolically distinct classes of ribonucleic acids in animal cells and its bearings on cancer. Nature. 1960 Apr 16;186:215–217. doi: 10.1038/186215a0. [DOI] [PubMed] [Google Scholar]
  19. SINSHEIMER R. L., LAWRENCE M. IN VITRO SYNTHESIS AND PROPERTIES OF A PHI-X DNA-RNA HYBRID. J Mol Biol. 1964 Feb;8:289–296. doi: 10.1016/s0022-2836(64)80138-8. [DOI] [PubMed] [Google Scholar]
  20. STENT G. S. Mating in the reproduction of bacterial viruses. Adv Virus Res. 1958;5:95–149. doi: 10.1016/s0065-3527(08)60672-7. [DOI] [PubMed] [Google Scholar]
  21. Spiegelman S., Hall B. D., Storck R. THE OCCURRENCE OF NATURAL DNA-RNA COMPLEXES IN E. COLI INFECTED WITH T2. Proc Natl Acad Sci U S A. 1961 Aug;47(8):1135–1141. doi: 10.1073/pnas.47.8.1135. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. WARNER R. C., SAMUELS H. H., ABBOTT M. T., KRAKOW J. S. Ribonucleic acid polymerase of Azotobacter vinelandii, II. Formation of DNA-RNA hybrids with single-stranded DNA as primer. Proc Natl Acad Sci U S A. 1963 Apr;49:533–538. doi: 10.1073/pnas.49.4.533. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. YANKOFSKY S. A., SPIEGELMAN S. The identification of the ribosomal RNA cistron by sequence complementarity. I. Specificity of complex formation. Proc Natl Acad Sci U S A. 1962 Jun 15;48:1069–1078. doi: 10.1073/pnas.48.6.1069. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Proceedings of the National Academy of Sciences of the United States of America are provided here courtesy of National Academy of Sciences

RESOURCES