Skip to main content
Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1964 Dec;52(6):1396–1402. doi: 10.1073/pnas.52.6.1396

ALTERATIONS IN CELLULAR METABOLISM ASSOCIATED WITH CELL DEATH INDUCED BY URACIL MUSTARD AND 6-THIOGUANINE*

Barbara A Booth 1, William A Creasey 1, Alan C Sartorelli 1
PMCID: PMC300458  PMID: 14243513

Full text

PDF
1396

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ALEXANDER P. The reactions of carcinogens with macromolecules. Adv Cancer Res. 1954;2:1–72. doi: 10.1016/s0065-230x(08)60491-1. [DOI] [PubMed] [Google Scholar]
  2. BOLLUM F. J., SETLOW R. B. Ultraviolet inactivation of DNA primer activity. I. Effects of different wavelengths and doses. Biochim Biophys Acta. 1963 Apr 30;68:599–607. doi: 10.1016/0006-3002(63)90189-6. [DOI] [PubMed] [Google Scholar]
  3. BOOTH B. A., SARTORELLI A. C. GROWTH INHIBITION OF A SPECTRUM OF TRANSPLANTED MOUSE TUMORS BY COMBINATIONS OF INHIBITORS OF NUCLEIC ACID BIOSYNTHESIS AND ALKYLATING AGENTS. Cancer Res. 1963 Dec;23:1762–1768. [PubMed] [Google Scholar]
  4. BOOTH B. A., SARTORELLI A. C. Sarcoma 180 inhibition by combinations of 6-thioguanine and uracil mustard. Science. 1962 Oct 26;138(3539):518–519. doi: 10.1126/science.138.3539.518. [DOI] [PubMed] [Google Scholar]
  5. BREWER H. B., Jr, COMSTOCK J. P., ARONOW L. Effects of nitrogen mustard on protein and nucleic acid synthesis in mouse fibroblasts growing in vitro. Biochem Pharmacol. 1961 Nov;8:281–287. doi: 10.1016/0006-2952(61)90102-2. [DOI] [PubMed] [Google Scholar]
  6. BUSCH H., AMER S. M., NYHAN W. L. Inhibition of uptake of Larginine-U-C14 into nuclear proteins by 5-bis (2-chloroethyl) aminouracil. J Pharmacol Exp Ther. 1959 Nov;127:195–199. [PubMed] [Google Scholar]
  7. BYVOET P., BUSCH H. Intracellular distribution of 5-bis(2-chloroethyl) aminouracil-2-C-14 in tissues of tumor-bearing rats. Cancer Res. 1962 Feb;22:249–253. [PubMed] [Google Scholar]
  8. Brookes P., Lawley P. D. The reaction of mono- and di-functional alkylating agents with nucleic acids. Biochem J. 1961 Sep;80(3):496–503. doi: 10.1042/bj0800496. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. DANNEBERG P. B., MONTAG B. J., HEIDELBERGER C. Studies on fluorinated pyrimidines. IV. Effects on nucleic acid metabolism in vivo. Cancer Res. 1958 Apr;18(3):329–334. [PubMed] [Google Scholar]
  10. DAVIS J. R., HONIG G. R., BUSCH H. Inhibition of uptake of L-lysine-U-C-14 into chromatographic fractions of cationic nuclear proteins by 5-bis-(2'-chloroethyl)-aminouracil. Tex Rep Biol Med. 1961;19:761–768. [PubMed] [Google Scholar]
  11. HONIG G. R., DAVIS J. R., BUSCH H. Suppression of uptake of L-arginine-U-14C into chromatographically separated cationic nuclear proteins of tissues of tumour-bearing rats by 5-bis (2-chloroethyl) aminouracil. Biochem Pharmacol. 1961 Jun;6:233–240. doi: 10.1016/0006-2952(61)90135-6. [DOI] [PubMed] [Google Scholar]
  12. KAPLAN H. S., SMITH K. C., TOMLIN P. Radiosensitization of E. coli by purine and pyrimidine analogues incorporated in deoxyribonucleic acid. Nature. 1961 May 27;190:794–796. doi: 10.1038/190794a0. [DOI] [PubMed] [Google Scholar]
  13. LEPAGE G. A. Incorporation of 6-thioguanine into nucleic acids. Cancer Res. 1960 Apr;20:403–408. [PubMed] [Google Scholar]
  14. LEVIS A. G., SPANIO L., DENADAI A. RADIOMIMETIC EFFECTS OF A NITROGEN MUSTARD ON SURVIVAL , GROWTH, PROTEIN AND NUCLEIC ACID SYNTHESIS OF MAMMALIAN CELLS IN VITRO. Exp Cell Res. 1963 Jun;31:19–30. doi: 10.1016/0014-4827(63)90151-4. [DOI] [PubMed] [Google Scholar]
  15. MARSHAK A., VOGEL H. J. Microdetermination of purines and pyrimidines in biological materials. J Biol Chem. 1951 Apr;189(2):597–605. [PubMed] [Google Scholar]
  16. POWERS E. L., POMEROY J. H. Comparisons of the biological effects of ionizing radiations and certain alkylating agents in cell systems. Ann N Y Acad Sci. 1958 Apr 24;68(3):702–720. doi: 10.1111/j.1749-6632.1958.tb42635.x. [DOI] [PubMed] [Google Scholar]
  17. TYNER E. P., HEIDELBERGER C., LEPAGE G. A. Intracellular distribution of radioactivity in nucleic acid nucleotides and proteins following simultaneous administration of P32 and glycine-2-C14. Cancer Res. 1953 Feb;13(2):186–203. [PubMed] [Google Scholar]
  18. WHEELER G. P. Studies related to the mechanisms of action of cytotoxic alkylating agents: a review. Cancer Res. 1962 Jul;22:651–688. [PubMed] [Google Scholar]

Articles from Proceedings of the National Academy of Sciences of the United States of America are provided here courtesy of National Academy of Sciences

RESOURCES