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. Author manuscript; available in PMC: 2011 Oct 12.
Published in final edited form as: Biochemistry. 2010 Sep 15;49(40):8766–8778. doi: 10.1021/bi101050h

Table 2.

Equilibrium binding thermodynamics for IL-7 and IL-4 interactions

Interaction 1ΔGo
(kcal mol−1)
ΔHo
(kcal mol−1)
−TΔSo2
(kcal mol−1)
IL-7/IL-7R (EC) −7.2 ± 0.2 0.31 ± 0.09 −7.5 ± 0.2
IL-7/IL-7R (CHO) −9.9 ± 0.1 −0.079 ± 0.042 −9.8 ± 0.1
IL-4/IL-4R −13.5 ± 0.63 −0.88 ± 0.31 −12.6 ± 0.7
1

ΔGo reported at 298 K. Experiments were performed with 150 mM NaCl at pH 7.4.

2

Calculated using −TΔSo = ΔGo − ΔHo.

3

Value taken from Table 2 from (15).