Table 1.

Baseline (pre-transfusion) characteristics of TACO patients and matched controls.

Variables	Cases (n=51)	Controls (n=51)	Odds Ratio (95% CI)	P-Value
Age*,§	73 (57–81)	75 (64–82)
Gender, Female*,†	24 (47)	24 (47)
ICU admission diagnosis*
Gastrointestinal*,†	23 (45)	23 (45)
Cardiovascular*,†	14 (27)	14 (27)
Respiratory*,†	5 (10)	5 (10)
Hematology*,†	4 (8)	4 (8)
Genitourinary*,†	3 (6)	3 (6)
Metabolic*,†	1 (2)	1 (2)
Neurology*,†	1 (2)	1 (2)
Race (White)†	48(94.1)	47(92.2)	1.3 (0.3,6.0)	0.706
PBV§	5 (4.3–5.6)	4.8(3.9–5.4)	1.26 (0.90,1.83)	0.189
APACHE III score‡,§	24(17–41)	24(16–42)	1.0(0.98, 1.02)	0.936
Smoke†	28(54.9%)	25(49%)	1.21 (0.60,2.46)	0.591
Alcohol Abuse†	9(17.6%)	5(9.8%)	3 (0.61,14.86)	0.178
Aspiration†	2(3.9%)	5(9.8%)	0.4 (0.08,2.06)	0.273
Sepsis†	10(19.6%)	9(17.6%)	1.2 (0.37,3.93)	0.763
Chronic anemia†	9(17.6%)	6(11.8%)	1.5 (0.53,4.21)	0.442
Diabetes†	16(31.4%)	17(33.3%)	0.9 (0.37,2.21)	0.819
Hypertension†	19(37.3%)	24(47.1%)	0.67 (0.30,1.48)	0.321
Chronic kidney disease†	10(19.6%)	13(25.5%)	0.7 (0.27,1.84)	0.469

IQR: 25% – 75% interquartile range; PBV: Predicted Body Volume; ICU: intensive care unit; ACEI: Angiotensin Converting Enzyme Inhibitors.

^*Matched pairs and no comparisons;

^†Number (%);

^‡APACHE III score: Acute Physiology and Chronic Health Evaluation score 1 hour after admission;

^§Median (25% – 75% interquartile range)