Skip to main content
PMC home page
Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1964 Jan;51(1):66–73. doi: 10.1073/pnas.51.1.66

TRANSFORMATION OF PROPERTIES OF AN ESTABLISHED CELL LINE BY SV40 AND POLYOMA VIRUS*

George J Todaro 1, Howard Green 1, Burton D Goldberg 1
PMCID: PMC300605  PMID: 14104605

Full text

PDF
66

Images in this article

67Image
on p.67
68Image
on p.68
69Image
on p.69
70Image
on p.70
71Image
on p.71
71Image
on p.71

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ABERCROMBIE M., HEAYSMAN J. E. Observations on the social behaviour of cells in tissue culture. I. Speed of movement of chick heart fibroblasts in relation to their mutual contacts. Exp Cell Res. 1953 Sep;5(1):111–131. doi: 10.1016/0014-4827(53)90098-6. [DOI] [PubMed] [Google Scholar]
  2. ASHKENAZI A., MELNICK J. L. Tumorigencity of simian papovavirus SV40 and of virus-transformed cells. J Natl Cancer Inst. 1963 Jun;30:1227–1265. [PubMed] [Google Scholar]
  3. BLACK P. H., ROWE W. P. Transformation in hamster kidney monolayers by vacuolating virus, SV-40. Virology. 1963 Jan;19:107–109. doi: 10.1016/0042-6822(63)90031-x. [DOI] [PubMed] [Google Scholar]
  4. DEFENDI V. Effect of SV 40 virus immunization on growth of transplantable SV 40 and polyoma virus tumors in hamsters. Proc Soc Exp Biol Med. 1963 May;113:12–16. doi: 10.3181/00379727-113-28261. [DOI] [PubMed] [Google Scholar]
  5. DEFENDI V., LEHMAN J., KRAEMER P. "Morphologically normal" hamster cells with malignant properties. Virology. 1963 Apr;19:592–598. doi: 10.1016/0042-6822(63)90058-8. [DOI] [PubMed] [Google Scholar]
  6. EAGLE H., OYAMA V. I., LEVY M., FREEMAN A. E. Myo-Inositol as an essential growth factor for normal and malignant human cells in tissue culture. J Biol Chem. 1957 May;226(1):191–205. [PubMed] [Google Scholar]
  7. GOLDBERG B., GREEN H., TODARO G. J. COLLAGEN FORMATION IN VITRO BY ESTABLISHED MAMMALIAN CELL LINES. Exp Cell Res. 1963 Aug;31:444–447. doi: 10.1016/0014-4827(63)90025-9. [DOI] [PubMed] [Google Scholar]
  8. HABEL K. Resistance of polyoma virus immune animals to transplanted polyoma tumors. Proc Soc Exp Biol Med. 1961 Apr;106:722–725. doi: 10.3181/00379727-106-26453. [DOI] [PubMed] [Google Scholar]
  9. MACPHERSON I., STOKER M. Polyoma transformation of hamster cell clones--an investigation of genetic factors affecting cell competence. Virology. 1962 Feb;16:147–151. doi: 10.1016/0042-6822(62)90290-8. [DOI] [PubMed] [Google Scholar]
  10. PONTEN J., JENSEN F., KOPROWSKI H. Morphological and virological investigation of human tissue cultures transformed with SV40. J Cell Comp Physiol. 1963 Apr;61:145–163. doi: 10.1002/jcp.1030610206. [DOI] [PubMed] [Google Scholar]
  11. PROCKOP D. J., UDENFRIEND S. A specific method for the analysis of hydroxyproline in tissues and urine. Anal Biochem. 1960 Nov;1:228–239. doi: 10.1016/0003-2697(60)90050-6. [DOI] [PubMed] [Google Scholar]
  12. RABSON A. S., KIRSCHSTEIN R. L. Induction of malignancy in vitro in newborn hamster kidney tissue infected with simian vacuolating virus (SV40). Proc Soc Exp Biol Med. 1962 Nov;111:323–328. doi: 10.3181/00379727-111-27780. [DOI] [PubMed] [Google Scholar]
  13. SACHS L., MEDINA D. In vitro transformation of normal cells by polyoma virus. Nature. 1961 Feb 11;189:457–458. doi: 10.1038/189457a0. [DOI] [PubMed] [Google Scholar]
  14. SANFORD K. K., DUNN T. B., COVALESKY A. B., DUPREE L. T., EARLE W. R. Polyoma virus and production of malignancy in vitro. J Natl Cancer Inst. 1961 Feb;26:331–357. [PubMed] [Google Scholar]
  15. SHEIN H. M., ENDERS J. F. Transformation induced by simian virus 40 in human renal cell cultures. I. Morphology and growth characteristics. Proc Natl Acad Sci U S A. 1962 Jul 15;48:1164–1172. doi: 10.1073/pnas.48.7.1164. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. TODARO G. J., GREEN H. Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. J Cell Biol. 1963 May;17:299–313. doi: 10.1083/jcb.17.2.299. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. TODARO G. J., NILAUSEN K., GREEN H. GROWTH PROPERTIES OF POLYOMA VIRUS-INDUCED HAMSTER TUMOR CELLS. Cancer Res. 1963 Jul;23:825–832. [PubMed] [Google Scholar]
  18. VOGT M., DULBECCO R. Steps in the neoplastic transformation of hamster embryo cells by polyoma virus. Proc Natl Acad Sci U S A. 1963 Feb 15;49:171–179. doi: 10.1073/pnas.49.2.171. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Vogt M., Dulbecco R. VIRUS-CELL INTERACTION WITH A TUMOR-PRODUCING VIRUS. Proc Natl Acad Sci U S A. 1960 Mar;46(3):365–370. doi: 10.1073/pnas.46.3.365. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Proceedings of the National Academy of Sciences of the United States of America are provided here courtesy of National Academy of Sciences

RESOURCES