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. 1964 Jan;51(1):89–97. doi: 10.1073/pnas.51.1.89

DEVELOPMENTAL HEMOGLOBIN ANOMALIES IN A CHROMOSOMAL TRIPLICATION: D1 TRISOMY SYNDROME*

E R Huehns 1,2,, F Hecht 1,2,, J V Keil 1,2, A G Motulsky 1,2,§
PMCID: PMC300609  PMID: 14104609

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BETKE K., MARTI H. R., SCHLICHT I. Estimation of small percentages of foetal haemoglobin. Nature. 1959 Dec 12;184(Suppl 24):1877–1878. doi: 10.1038/1841877a0. [DOI] [PubMed] [Google Scholar]
  2. BRANDT N. J., FROLAND A., MIKKELSEN M., NIELSEN A., TOLSTRUP N. GALACTOSAEMIA LOCUS AND THE DOWN'S SYNDROME CHROMOSOME. Lancet. 1963 Oct 5;2(7310):700–703. doi: 10.1016/s0140-6736(63)90345-3. [DOI] [PubMed] [Google Scholar]
  3. DANCE N., HUEHNS E. R., BEAVEN G. H. The abnormal haemoglobins in haemoglobin-H disease. Biochem J. 1963 May;87:240–248. doi: 10.1042/bj0870240. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. HECHT F., BRYANT J. S., MOTULSKY A. G., GIBLETT E. R. THE NO. 17-18 (E) TRISOMY SYNDROME. STUDIES ON CYTOGENETICS, DERMATOGLYPHICS, PATERNAL AGE, AND LINKAGE. J Pediatr. 1963 Oct;63:605–621. doi: 10.1016/s0022-3476(63)80371-6. [DOI] [PubMed] [Google Scholar]
  5. HORTON B. F., THOMPSON R. B., DOZY A. M., NECHTMAN C. M., NICHOLS E., HUISMAN T. H. Inhomogeneity of hemoglobin. VI. The minor hemoglobin components of cord blood. Blood. 1962 Sep;20:302–314. [PubMed] [Google Scholar]
  6. HUEHNS E. R., FLYNN F. V., BUTLER E. A., BEAVEN G. H. Two new haemoglobin variants in a very young human embryo. Nature. 1961 Feb 11;189:496–497. doi: 10.1038/189496a0. [DOI] [PubMed] [Google Scholar]
  7. HUEHNS E. R., SHOOTER E. M., BEAVEN G. H. On the recombination of canine and human haemoglobins. J Mol Biol. 1962 May;4:323–328. doi: 10.1016/s0022-2836(62)80012-6. [DOI] [PubMed] [Google Scholar]
  8. Itano H. A., Robinson E. A. GENETIC CONTROL OF THE alpha- AND beta-CHAINS OF HEMOGLOBIN. Proc Natl Acad Sci U S A. 1960 Nov;46(11):1492–1501. doi: 10.1073/pnas.46.11.1492. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. JONXIS J. H., VISSER H. K. Determination of low percentages of fetal hemoglobin in blood of normal children. AMA J Dis Child. 1956 Dec;92(6):588–591. doi: 10.1001/archpedi.1956.02060030582007. [DOI] [PubMed] [Google Scholar]
  10. KLEIHAUER E., BRAUN H., BETKE K. Demonstration von fetalem Hämoglobin in den Erythrocyten eines Blutausstrichs. Klin Wochenschr. 1957 Jun 15;35(12):637–638. doi: 10.1007/BF01481043. [DOI] [PubMed] [Google Scholar]
  11. MOORHEAD P. S., NOWELL P. C., MELLMAN W. J., BATTIPS D. M., HUNGERFORD D. A. Chromosome preparations of leukocytes cultured from human peripheral blood. Exp Cell Res. 1960 Sep;20:613–616. doi: 10.1016/0014-4827(60)90138-5. [DOI] [PubMed] [Google Scholar]
  12. MOTULSKY A. G. Controller genes in synthesis of human haemoglobin. Nature. 1962 May 12;194:607–609. doi: 10.1038/194607b0. [DOI] [PubMed] [Google Scholar]
  13. NEEL J. V. The hemoglobin genes: a remarkable example of the clustering of related genetic functions on a single mammalian chromosome. Blood. 1961 Dec;18:769–777. [PubMed] [Google Scholar]
  14. RANNEY H. M., JACOBS A. S., BRADLEY T. B., Jr, CORDOVA F. A. A 'new' variant of haemoglobin A2 and its segregation in a family with haemoglobin S. Nature. 1963 Jan 12;197:164–166. doi: 10.1038/197164a0. [DOI] [PubMed] [Google Scholar]
  15. RAPER A. B., GAMMACK D. B., HUEHNS E. R., SHOOTER E. M. Four haemoglobins in one individual. A study of the genetic interaction of Hb-G and Hb-C. Br Med J. 1960 Oct 29;2(5208):1257–1261. doi: 10.1136/bmj.2.5208.1257. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. ROBINSON A. R., ROBSON M., HARRISON A. P., ZUELZER W. W. A new technique for differentiation of hemoglobin. J Lab Clin Med. 1957 Nov;50(5):745–752. [PubMed] [Google Scholar]
  17. SCHROEDER W. A., CUA J. T., MATSUDA G., FENNINGER W. D. Hemoglobin F1, an acetyl-containing hemoglobin. Biochim Biophys Acta. 1962 Oct 8;63:532–534. doi: 10.1016/0006-3002(62)90125-7. [DOI] [PubMed] [Google Scholar]
  18. SMITH D. W., PATAU K., THERMAN E., INHORN S. L., DEMARS R. I. The D-I trisomy syndrome. J Pediatr. 1963 Mar;62:326–341. doi: 10.1016/s0022-3476(63)80129-8. [DOI] [PubMed] [Google Scholar]
  19. UCHIDA I. A., PATAU K., SMITH D. W. Dermal patterns of 18 and D1 trisomics. Am J Hum Genet. 1962 Dec;14:345–352. [PMC free article] [PubMed] [Google Scholar]
  20. WARKANY J., RUBINSTEIN J. H., SOUKUP S. W., CU RLESS M. C. Mental retardation, absence of patellae, other malformations with chromosomal mosiacism. J Pediatr. 1962 Dec;61:803–812. doi: 10.1016/s0022-3476(62)80191-7. [DOI] [PubMed] [Google Scholar]

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