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. Author manuscript; available in PMC: 2010 Dec 21.
Published in final edited form as: Biochemistry. 2008 Jan 31;47(8):2476–2484. doi: 10.1021/bi702109w

Figure 4.

Figure 4

Previously identified functions of the TRPV6-ARD mapped onto the structure. Sections identified as critical for channel assembly/tetramerization (residues 64–76 in TRPV5 (18), and residues 136–140 in TRPV6 (17)) are colored red and the regions of ankyrin repeats 3 and 5 assigned a role in channel assembly (residues 116–163 and 192–230; (17)) are colored yellow. The region previously implicated in CaM binding (residues 85–100; (27)) is colored purple. Side chains whose phosphorylation may regulate TRPV6 activity are colored orange.