Table 3. Renal neoplasms in patients with chronic uremia.
Case No. | Transplant or dialysis center | Age (years) |
Sex | Underlying renal disease | Type of tumor | Mode of presentation | Relationship to transplantation | Referring physician |
---|---|---|---|---|---|---|---|---|
1 | Minneapolis | 45 | F | Chronic glomerulonephritis | Hypernephroma of right kidney | Mass in upper pole of right kidney | Not transplanted; on hemodialysis | R. Simmons |
2 | San Francisco | 29 | M | Chronic glomerulonephritis | Renal cell carcinoma of left kidney invading capsule and perinephric fat | Incidental finding at bilateral nephrectomy | Twenty months before transplantation | F. Belzer |
3 | Cleveland | Not stated | Not stated | Not stated | Renal cell carcinoma involving a solitary kidney | Incidental finding at nephrectomy | Four weeks before transplantation | S. Nakamoto- |
4 | Edinburgh | Not stated | Not stated | Not stated | Hypernephroma of one of the kidneys | Incidental finding at bilateral nephrectomy for persistent hypertension | After transplantation | M. Woodruff |
5a | New York (Cornell) | 18 | M | End stage renal disease | Low grade papillary renal carcinoma of right kidney | Incidental finding when kidneys re moved | At the time of transplantation | R. Porro |
6a | Boston | 34 | M | Chronic glomerulonephritis | (1) Well differentiated renal cell carcinoma of left kidney; (2) two adenomas of right kidneyb | Incidental finding when kidneys removed | At the time of a second transplantation 3 months after insertion of a first homograft which never functioned | R. E. Wilson |
7 | Ann Arbor | 43 | M | End stage renal disease | Renal cell carcinoma of right kidney | Incidental finding when kidneys removed | At the time of transplantation | J. Turcotte |
8 | London | 44 | M | Hyperparathyroidism with nephrocalcinosis | Renal carcinoma of both kidneys | Incidental finding when kidneys removed | Ten months before transplantation | J. Salaman |
9 | Los Angeles | 35 | M | Malignant hypertension | Hypernephroma of a kidney | Massive retroperitoneal hemorrhage from the affected kidney | Fifteen months before transplantation | T. Berne |
10 | Dallas | 21 | M | Chronic glomerulonephritis | Renal cell carcinoma in one of his kidneys | Gross hematuria at age 18 years approximately 15 months alter immunosuppressive treatment with Imuran and prednisone was started; workup showed mass lesion in one kidney | Not transplanted; on chronic hemodialysis for approximately 3 years | P. Peters |
11 | Minneapolis | 48 | F | Chronic pyelonephritis | Adenoma of left kidneyb | Incidental finding at bilateral nephrectomy | Awaiting transplantation | R. Simmons |
12 | Tucson | 43 | M | Chronic glomerulonephritis | Adenoma of left kidneyb | Incidental finding at bilateral nephrectomy | Several weeks before transplantation | C. Zukoski |
These patients are cases 8 and 28 in Table 2.
There is considerable disagreement among pathologists concerning the difference between a large renal adenoma and a small renal carcinoma. A lesion less than 2 cm in diameter is often regarded as an adenoma and a larger lesion is often regarded as a carcinoms.