Table 3.
Infectivity of X/P-MLVs and XMRV on cells of mammalian species
| Log10 Titer* | |||||
|---|---|---|---|---|---|
| Cells | CAST-X X-MLV | XMRV | Cz524 | CasE#1 | MoMCF P-MLV |
| M. dunni | +++ | +++ | +++ | +++ | +++ |
| Human 293 | +++ | +++ | +++ | +++ | +++ |
| Monkey COS-1 | +++ | +++ | +++ | +++ | +++ |
| Ferret | +++ | +++ | +++ | +++ | +++ |
| Rabbit SIRC | +++ | ++ | +++ | +++ | ++ |
| Cat CRFK | +++ | +++ | +++ | +++ | +++ |
| Bat Tb-1-Lu | +++ | ++ | +++ | +++ | - |
| Guinea pig JH4 | +++ | ++ | ++ | - | - |
| Goat | +++ | ++ | + | - | - |
| Buffalo | +++ | + | - | - | - |
| Dog MDCK | +++ | ++ | - | - | - |
| Gerbil GeLu | +++ | - | - | - | - |
| Chinese hamster Lec8 | +++ | - | - | - | - |
*Infectivity measured as the number of β-galactosidase-positive cells in 50 μl of viral pseudotypes carrying the LacZ reporter. Log10 titer: +++, >3; ++, 2-3; +, 1-2; -, 0-1. [101]. Hamster Lec8 cells have a glycosylation defect that relieves resistance to some X-MLVs.