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Indian Journal of Psychiatry logoLink to Indian Journal of Psychiatry
. 1985 Oct-Dec;27(4):325–328.

SERUM IMMUNOGLOBULINS AND SCHIZOPHRENIA1

IVL Narasimha Rao 2, PS Gopinath 3, N Jayasimha 4, BS Sridhara Rama Rao 5, DK Subbakrishna 6
PMCID: PMC3010718  PMID: 21927129

SUMMARY

Fifty four schizophrenic patients, diagnosed as per Research Diagnostic Criteria, were studied for immunoglobulin profiles. The schizophrenics were subdivided into paranoid and non-paranoid groups and their immunoglobulin profiles were compared with those of normals. There was no significant difference between normals and schizophrenic groups. Duration of illness, previous episodes of schizopnrenia, family history of schizophrenia severity of psychosis and duration of hospital stay had no influence on serum IgG, IgA and IgM in schizophrenics. The results are discussed in the light of existing literature on immunoglobulin alterations in schizophrenia.

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