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Dose-response effect on the fibrous tissues surrounding the implanted hydrogels containing rosiglitazone.
| Rosiglitazone Dose | Capsule Density | Average Capsule Thickness | Collagen Deposition |
|---|---|---|---|
| 0 | 3.0±0 | 10.9±3.0 (range: 7.4 to 12.0) | +++ |
| 0.67 μg | 2.2±0.5 | 7.7±1.1 (range: 6.1 to 8.6) | + |
| 6.7 μg | 1.5±0.5 | 7.2±1.5 (range: 5.9 to 9.3) | None |
